Publication
Individual motions of red blood cells in high-hematocrit blood flowing in a microchannel with complex geometries
| dc.contributor.author | Ishikawa, Takuji | |
| dc.contributor.author | Fujiwara, Hiroki | |
| dc.contributor.author | Matsuki, Noriaki | |
| dc.contributor.author | Lima, Rui A. | |
| dc.contributor.author | Imai, Yohsuke | |
| dc.contributor.author | Ueno, H. | |
| dc.contributor.author | Yamaguchi, Takami | |
| dc.date.accessioned | 2010-01-27T20:11:23Z | |
| dc.date.available | 2010-01-27T20:11:23Z | |
| dc.date.issued | 2009 | |
| dc.description.abstract | Blood flow in a microchannel with complex geometries has been investigated to develop biomedical microdevices (e.g. Faivre et al., 2006) or to understand pathology in small vessels, such as lacunar infarcts. In a small channel, say 100 μm in diameter, the blood is no longer assumed to be a homogeneous fluid because the size of the red blood cells (RBCs) cannot be neglected compared to the generated flow field (the diameter of a RBC is about 8 μm). In such a case, we must treat the blood as a multiphase fluid, and investigate the motion of individual cells in discussing the flow field. In this study, we investigated the motion of RBCs in a microchannel with stenosis or bifurcation using a confocal micro-PTV system. We measured individual trajectories of RBCs under high Hct conditions (up to 20%), when the interactions between RBCs become significant. We discuss the effect of Hct on the flow field and cell-free layers, as well as the effect of deformability of RBCs on the cell-free layer thickness by hardening RBCs using a glutaraldehyde treatment. | pt |
| dc.identifier.citation | Ishikawa, T.; Fujiwara, H.; Matsuki, N.; Lima, R.; Imai, Y.; Ueno, H.; Yamaguchi, T.(2009) - Individual motions of red blood cells in high-hematocrit blood flowing in a microchannel with complex geometries. Proceeding of the ASME. Orlando, USA. | pt |
| dc.identifier.uri | http://hdl.handle.net/10198/1553 | |
| dc.language.iso | eng | pt |
| dc.publisher | ASME | pt |
| dc.subject | Red blood cell | pt |
| dc.subject | Microcirculation | pt |
| dc.title | Individual motions of red blood cells in high-hematocrit blood flowing in a microchannel with complex geometries | pt |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Orlando, USA | pt |
| oaire.citation.title | Proceeding of the ASME 2009 (SBC2009) | pt |
| person.familyName | Lima | |
| person.givenName | Rui A. | |
| person.identifier.ciencia-id | EE12-C3FB-349D | |
| person.identifier.orcid | 0000-0003-3428-637X | |
| person.identifier.rid | H-5157-2016 | |
| person.identifier.scopus-author-id | 18437397800 | |
| rcaap.rights | openAccess | pt |
| rcaap.type | conferenceObject | pt |
| relation.isAuthorOfPublication | 7b50c499-8095-4f4f-8b1b-fa7388e4ff62 | |
| relation.isAuthorOfPublication.latestForDiscovery | 7b50c499-8095-4f4f-8b1b-fa7388e4ff62 |