Publication
Antioxidant capacity and toxicological evaluation of pterospartum tridentatum flower extracts
| dc.contributor.author | Ferreira, Fernanda M. | |
| dc.contributor.author | Dinis, Lia Tânia | |
| dc.contributor.author | Azedo, Pedro | |
| dc.contributor.author | Galhano, Cristina | |
| dc.contributor.author | Cardoso, Susana M. | |
| dc.contributor.author | Domingues, Maria R.M. | |
| dc.contributor.author | Pereira, Olívia R. | |
| dc.contributor.author | Simões, Anabela | |
| dc.contributor.author | Palmeira, Carlos M. | |
| dc.contributor.author | Peixoto, Francisco P. | |
| dc.date.accessioned | 2012-05-14T15:08:22Z | |
| dc.date.available | 2012-05-14T15:08:22Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | Pterospartum tridentatum Willk. (prickled broom) is an autochthonous plant, common in Portuguese territory. The yellow flowers are used in traditional medicine, as a potential cure for all body illnesses, mainly for throat irritation treatment or for diabetes, hypertension and hypercholesterolemia therapy.Despite its traditional use, no toxicological assessment has been performed as we know. A high antioxidant activity of P. tridentatum flower water extract was acessed in good agreement with its ESI-MS spectrum that revealed the presence of several flavonoids, as luteolin-O-(O-acetyl)-glucuronide, luteolin-O- glucuronide or isorhamnetin-O-hexoside. Mitocondrial respiratory rates (state 4, state 3 and FCCP-stimulated respiration) and respiratory indexes (respiratory control and P/O ratios) showed no consistent decrease of respiratory and phosphorylative efficiencies for the concentrations tested (up to 500 μg.mL-1). Cytotoxicity evaluation, using MTT assay, was reliable with the previous results. In conclusion, for the concentration range commonly used P. tridentatum flowers usage can be regarded as harmless and trustworthy. | por |
| dc.identifier.citation | Ferreira, Fernanda; Dinis, Lia; Azedo, Pedro; Galhano, Cristina; Cardoso, Susana; Domingues, M. Rosário; Pereira, Olívia R.; Simões, Anabela; Palmeira, Carlos; Peixoto, Francisco (2012). Antioxidant capacity and toxicological evaluation of pterospartum tridentatum flower extracts. CyTA - Journal of Food. ISSN 1947-6337. 10:2, p. 92-102 | por |
| dc.identifier.doi | 10.1080/19476337.2011.590233 | |
| dc.identifier.uri | http://hdl.handle.net/10198/6900 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Taylor & Francis | por |
| dc.subject | Antioxidant capacity | por |
| dc.subject | Oxidative phosphorylation | por |
| dc.subject | Cytotoxicity | por |
| dc.subject | Pterospartum tridentatum (L.) Willk. | por |
| dc.subject | Toxicologic evaluation | por |
| dc.subject | Phytotherapy | por |
| dc.title | Antioxidant capacity and toxicological evaluation of pterospartum tridentatum flower extracts | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | London | por |
| oaire.citation.title | CyTA Journal of Food | por |
| person.familyName | Pereira | |
| person.givenName | Olívia R. | |
| person.identifier | 145216 | |
| person.identifier.ciencia-id | B312-AF21-D2FA | |
| person.identifier.orcid | 0000-0002-6275-3134 | |
| person.identifier.rid | H-1049-2014 | |
| person.identifier.scopus-author-id | 52264387000 | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
| relation.isAuthorOfPublication | e8fdab9a-3ad6-47e6-b90c-7a37aabcb453 | |
| relation.isAuthorOfPublication.latestForDiscovery | e8fdab9a-3ad6-47e6-b90c-7a37aabcb453 |