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Polyols based solvents for the extraction of phenolic compounds from Juglans regia L. leaves.

dc.contributor.authorVieira, Vanessa
dc.contributor.authorPrieto Lage, Miguel A.
dc.contributor.authorBarros, Lillian
dc.contributor.authorCoutinho, João A.P.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorFerreira, Olga
dc.date.accessioned2018-02-12T10:32:16Z
dc.date.available2018-02-12T10:32:16Z
dc.date.issued2017
dc.description.abstractIn this work, a set of polyols was selected to be used as solvents for the extraction of phenolic compounds from Juglans regia L. (walnut) leaves. Their biocompatibility and low toxicity makes them an interesting option with potential industrial applications in the cosmetic, pharmaceutical or food areas. In fact, some of them are already used as cosmetic ingredients and/or can be obtained from renewable raw materials [1, 2]. Walnut leaves are an important source of bioactive molecules, such as phenolic compounds, suggesting that their extracts (or pure components) could be used as natural antioxidants in different applications, e.g. to replace synthetic antioxidants such as BHT (2,6-di-tert-butyl-4-methylphenol) or in dermatological bases preventing oxidative damage [3,4]. Hence, the extraction performance of glycerol and a series of diols (1,2-etanodiol, 1,2-propanediol, 1,3- propanediol, 1,3-butanediol, 1,2-pentanediol, 1,5-pentanediol, 1,2-hexanediol, 1,6-hexanediol) was screened and the phenolic profile, characterized by HPLC-DAD. To evaluate the response, only the main bioactive compounds present in the extract (acid 3-O-caffeyloquinic acid, quercetin 3-O-glucoside and quercetin O-pentoside) were considered. In a second phase, for comparison purposes, the most promising polyols were selected to prepare betaine based deep eutectic mixtures. After selecting the best solvent, the remaining extraction conditions (time, temperature and water content) were further optimized. These results provide relevant information for the design of an extraction process of phenolic compounds from J. regia leaves using alternative solvents that could also play a role as a formulation medium.pt_PT
dc.description.sponsorshipCICECO, for financial support to Project UID/CTM/50011/2013 and PTDC/AGR-TEC/1191/2014. CIMO, for financial support to Project UID/AGR/00690/2013. LSRE-LCM for financial support to Project POCI-01-0145-FEDER-006984. To Xunta de Galicia, for financial support for the post-doctoral researcher of M.A. Prieto. The authors thank the Foundation for Science and Technology (FCT, Portugal) Vanessa Vieira research grant SFRH/BD/108487/2015.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationVieira, Vanessa; Prieto, Miguel; Barros, Lillian; Coutinho, João A.P.; Ferreira, Isabel C.F.R.; Ferreira, Olga (2017). Polyols based solvents for the extraction of phenolic compounds from Juglans regia L. leaves. In 10º Encontro Nacional de Cromatografia. Bragança. ISBN 978-972-745-234-7pt_PT
dc.identifier.isbn978-972-745-234-7
dc.identifier.urihttp://hdl.handle.net/10198/15666
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherInstituto Politécnico de Bragançapt_PT
dc.relationNatural Deep Eutectic Solvents: A platform to Boost Eucalyptus globulus and Quercus suber cork integrated Biorefineries
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titlePolyols based solvents for the extraction of phenolic compounds from Juglans regia L. leaves.pt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleNatural Deep Eutectic Solvents: A platform to Boost Eucalyptus globulus and Quercus suber cork integrated Biorefineries
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FAGR-TEC%2F1191%2F2014/PT
oaire.citation.conferencePlaceBragança, Portugalpt_PT
oaire.citation.title10º Encontro Nacional de Cromatografiapt_PT
oaire.fundingStream5876
oaire.fundingStream9471 - RIDTI
person.familyNamePrieto Lage
person.familyNameBarros
person.familyNameFerreira
person.familyNameFerreira
person.givenNameMiguel A.
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.givenNameOlga
person.identifier107688
person.identifier469085
person.identifier144781
person.identifier.ciencia-id221E-1E00-AB74
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id9F1D-C75A-4A54
person.identifier.orcid0000-0002-3513-0054
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0001-8414-3479
person.identifier.ridG-4516-2011
person.identifier.ridJ-3600-2013
person.identifier.ridE-8500-2013
person.identifier.ridM-4567-2013
person.identifier.scopus-author-id35937495700
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id57203083219
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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