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Polyphenols characterization and toxicological evaluation of pterospartum tridentatum leaf water extracts

2012Conference object Open access
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dc.contributor.authorFerreira, Fernanda M.
dc.contributor.authorPeixoto, Francisco P.
dc.contributor.authorPereira, Olívia R.
dc.contributor.authorDinis, Lia Tânia
dc.contributor.authorDomingues, Maria R.M.
dc.contributor.authorPalmeira, Carlos M.
dc.contributor.authorCardoso, Susana M.
dc.date.accessioned2013-10-10T10:40:05Z
dc.date.available2013-10-10T10:40:05Z
dc.date.issued2012
dc.description.abstractPterospartum tridentatum Willk. (prickled broom) is an autochthonous and common plant in Portugal. Leaves and stems are normally used in cooking, to flavour rice, roast meat or hunting animals. Leaves are also used as a condiment in fresh salads and, despite of its traditional use, no toxicological evaluation has been performed. P. tridentatum leaves aqueous extract ESI-MS spectrum revealed the presence of several luteolin and isorhamnetin derived phenolic compounds, which can be associated to the health benefits claimed for this plant species. Still, P. tridentatum leaves extract (up to 100 µg plant extract.mg-1 protein) stimulated state 4 and FCCP-stimulated liver mitochondria respiratory rates and inhibited the state 3 respiratory rate. Respiratory control ratio was diminished, indicating a decrease in phosphorylative efficiency due to inner mitochondrial membrane induced by P. tridentatum leaves extract. Nevertheless, previous results, cytotoxicity evaluation by MTT assay (50 and 125 µg plant extract) showed no significant decrease on HepG2 cell viability. Overall, the present study suggests that the consumption of P. tridentatum leaves should be regarded as safe.por
dc.identifier.citationFerreira, Fernanda M.; Peixoto, Francisco P.; Pereira, Olívia R.; Dinis, Lia T.; Domingues, M. R. M.; Palmeira, Carlos M.; Cardoso, Susana M.(2012) - Polyphenols characterization and toxicological evaluation of pterospartum tridentatum leaf water extracts. In XVIII Encontro Luso-Galego de Química. Vila Realpor
dc.identifier.urihttp://hdl.handle.net/10198/8895
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherUTAD - Universidade de Trás-os-Montes e Alto Douropor
dc.subjectPterospartum tridentatum Willk.por
dc.subjectToxicological evaluationpor
dc.subjectPhenolic characterizationpor
dc.titlePolyphenols characterization and toxicological evaluation of pterospartum tridentatum leaf water extractspor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceVila Real, Portugalpor
oaire.citation.titleXVIII Encontro Luso-Galego de Químicapor
person.familyNamePereira
person.givenNameOlívia R.
person.identifier145216
person.identifier.ciencia-idB312-AF21-D2FA
person.identifier.orcid0000-0002-6275-3134
person.identifier.ridH-1049-2014
person.identifier.scopus-author-id52264387000
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublicatione8fdab9a-3ad6-47e6-b90c-7a37aabcb453
relation.isAuthorOfPublication.latestForDiscoverye8fdab9a-3ad6-47e6-b90c-7a37aabcb453

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