Publication
Low cost microfluidic device for partial cell separation: micromilling approach
| dc.contributor.author | Lopes, Raquel | |
| dc.contributor.author | Rodrigues, Raquel Oliveira | |
| dc.contributor.author | Pinho, Diana | |
| dc.contributor.author | Valdemar, Garcia | |
| dc.contributor.author | Schütte, Helmut | |
| dc.contributor.author | Lima, Rui A. | |
| dc.contributor.author | Gassmann, Stefan | |
| dc.date.accessioned | 2015-07-31T10:18:22Z | |
| dc.date.available | 2015-07-31T10:18:22Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | Several studies have already demonstrated that it is possible to perform blood flow studies in microfluidic systems fabricated by using low-cost techniques. However, most of these techniques do not produce microchannels smaller than 100 microns and as a result they have several limitations related to blood cell separation. Recently, manufacturers have been able to produce milling tools smaller than 100 microns, which consequently have promoted the ability of micromilling machines to fabricate microfluidic devices able to perform separation of red blood cells (RBCs) from plasma. In this work, we show the ability of a micromilling machine to manufacture microchannels with dimensions down to 30 microns. Additionally, we show for the first time the ability of the proposed microfluidic device to enhance the cell-free layer close to the walls, leading to perform partial separation of RBCs from plasma. | por |
| dc.description.sponsorship | The authors acknowledge the financial support provided by PTDC/SAU-ENB/116929/2010 and EXPL/EMSSIS/ 2215/2013 from FCT (Science and Technology Foundation), COMPETE, QREN and European Union (FEDER). RR and DP acknowledge, respectively, the PhD scholarships SFRH/BD/97658/2013 and SFRH/BD/89077/2012 attributed by FCT. | |
| dc.identifier.citation | Lopes, Raquel; Rodrigues, Raquel O. ; Pinho, Diana; Garcia, Valdemar; Schutte, Helmut; Lima, Rui; Gassmann, Stefan (2015) . Low cost microfluidic device for partial cell separation: micromilling approach. In 2015 IEEE International Conference on Industrial Technology, ICIT 2015. Seville. p. 3347-3350. ISBN 978-1-4799-7800-7 | por |
| dc.identifier.doi | 10.1109/ICIT.2015.7125594 | |
| dc.identifier.isbn | 978-1-4799-7800-7 | |
| dc.identifier.uri | http://hdl.handle.net/10198/12014 | |
| dc.language.iso | por | por |
| dc.peerreviewed | yes | por |
| dc.publisher | IEEE | por |
| dc.relation | BIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability | |
| dc.relation | MAGNETIC CARBON NANOSTRUCTURES AND STUDY OF THEIR TRANSPORT IN MICROFLUIDIC DEVICES FOR HYPERTHERMIA | |
| dc.subject | Micromilling | por |
| dc.subject | Microfluidic device | por |
| dc.subject | Nonlithographic technique | por |
| dc.subject | Red blood cells | por |
| dc.subject | Cell-free layer | por |
| dc.title | Low cost microfluidic device for partial cell separation: micromilling approach | por |
| dc.type | conference paper | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | BIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability | |
| oaire.awardTitle | MAGNETIC CARBON NANOSTRUCTURES AND STUDY OF THEIR TRANSPORT IN MICROFLUIDIC DEVICES FOR HYPERTHERMIA | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FSAU-ENB%2F116929%2F2010/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/COMPETE/EXPL%2FEMS-SIS%2F2215%2F2013/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F97658%2F2013/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F89077%2F2012/PT | |
| oaire.citation.conferencePlace | Seville, Spain | por |
| oaire.citation.endPage | 3350 | por |
| oaire.citation.startPage | 3347 | por |
| oaire.citation.title | Industrial Technology | por |
| oaire.fundingStream | 5876-PPCDTI | |
| oaire.fundingStream | COMPETE | |
| oaire.fundingStream | SFRH | |
| person.familyName | Pinho | |
| person.familyName | Lima | |
| person.givenName | Diana | |
| person.givenName | Rui A. | |
| person.identifier.ciencia-id | 5214-ED0C-35E8 | |
| person.identifier.ciencia-id | EE12-C3FB-349D | |
| person.identifier.orcid | 0000-0002-3884-6496 | |
| person.identifier.orcid | 0000-0003-3428-637X | |
| person.identifier.rid | H-5157-2016 | |
| person.identifier.scopus-author-id | 18437397800 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | por |
| rcaap.type | conferenceObject | por |
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