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Determination of neutrophil Fcc receptor IIIb antigens (HNA-1a, HNA-1b and HNA-1c) by fluorescence-primed allele-specific polymerase chain reaction

dc.contributor.authorCosta, Elísio
dc.contributor.authorAntunes, Marika Bini
dc.contributor.authorFaria, Susana
dc.contributor.authorVieira, Emília
dc.contributor.authorBranca, Rosa
dc.contributor.authorBarbot, José
dc.contributor.authorSantos, Rosário
dc.date.accessioned2008-02-21T10:12:03Z
dc.date.available2008-02-21T10:12:03Z
dc.date.issued2004
dc.description.abstractWe evaluate a technique for genotyping HNA-1a, -1b and -1c antigens, resorting to fluorescence-primed allele-specific polymerase chain reaction (FPAS-PCR), and determine the frequency of the different genotypes in a normal Portuguese population. Our results indicate that the FPAS-PCR system is a reliable and simple tool for genotyping the neutrophil Fcc receptor IIIB antigens. The HNA-1a, -1b and -1c gene frequencies of 42.98, 84.21 and 6.14%, respectively, found in this study are similar to those reported for other white populations.en
dc.identifier.citationCosta, Elísio; Antunes, Marika Bini; Faria, Susana; Vieira, Emília; Branca, Rosa; Barbot, José; Santos, Rosário (2004). Determination of neutrophil Fcc receptor IIIb antigens (HNA-1a, HNA-1b and HNA-1c) by fluorescence-primed allele-specific polymerase chain reaction. Clinical and Laboratory Haematology. ISSN 1365-2257. 26:5, p. 319–321en
dc.identifier.issn1365-2257
dc.identifier.urihttp://hdl.handle.net/10198/507
dc.language.isoengen
dc.subjectFccRIIIB antigensen
dc.subjectNeutrophilen
dc.titleDetermination of neutrophil Fcc receptor IIIb antigens (HNA-1a, HNA-1b and HNA-1c) by fluorescence-primed allele-specific polymerase chain reactionen
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccess
rcaap.typearticleen

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