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Cholesterol-based compounds: Recent advances in synthesis and applications

2019Journal article Open access
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dc.contributor.authorAlbuquerque, Hélio
dc.contributor.authorSantos, Clementina M.M.
dc.contributor.authorSilva, Artur
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2019-01-28T11:57:52Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2019-01-28T11:57:52Z
dc.date.issued2019
dc.description.abstractThis review reports on the latest developments (since 2014) in the chemistry of cholesterol and its applications in different research fields. These applications range from drug delivery or bioimaging applications to cholesterol-based liquid crystals and gelators. A brief overview of the most recent synthetic procedures to obtain new cholesterol derivatives is also provided, as well as the latest anticancer, antimicrobial, and antioxidant new cholesterol-based derivatives. This review discusses not only the synthetic details of the preparation of new cholesterol derivatives or conjugates, but also gives a short summary concerning the specific application of such compounds
dc.description.sponsorshipThanks are due to the University of Aveiro, Instituto Politécnico de Bragança, FCT/MEC for financial support of the QOPNA (FCT UID/QUI/00062/2013) and CIMO (UID/AGR/00690/2013) research units, through national funds, and where applicable cofinanced by the FEDER, within the PT2020 Partnership Agreement; and also to the Portuguese NMR Network. This work was also supported by the Integrated Programme of SR&TD “pAGE–Protein aggregation Across the Lifespan” (reference CENTRO-01-0145-FEDER-000003), co-funded by the Centro 2020 program, Portugal 2020, European Union, through the European Regional Development Fund. H. M. T. Albuquerque thanks the pAGE project for his Post-Doc grant (BPD/UI98/4861/2017).
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationAlbuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur (2019). Cholesterol-based compounds: Recent advances in synthesis and applications. Molecules. ISSN 1420-3049. 24:1, p. 1-68en_EN
dc.identifier.doi10.3390/molecules24010116en_EN
dc.identifier.urihttp://hdl.handle.net/10198/8497
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relationBPD/UI98/4861/2017
dc.subjectBioactive compoundsen_EN
dc.subjectBioimagingen_EN
dc.subjectCholesterolen_EN
dc.subjectDrug deliveryen_EN
dc.subjectGelatorsen_EN
dc.subjectLiquid crystalsen_EN
dc.subjectSynthesisen_EN
dc.titleCholesterol-based compounds: Recent advances in synthesis and applicationsen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FQUI%2F00062%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.fundingStream5876
oaire.fundingStream5876
person.familyNameSantos
person.givenNameClementina M.M.
person.identifier.ciencia-id9018-DB9C-C590
person.identifier.orcid0000-0003-4380-7990
person.identifier.scopus-author-id7201458663
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
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relation.isAuthorOfPublication.latestForDiscovery64f662b6-775d-4ea0-bfd7-f527af0ac1a0
relation.isProjectOfPublicationa955d531-2af9-40df-baaf-a064d8a697e9
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