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Advisor(s)
Abstract(s)
Microfluidic devices are becoming one of the
most promising new tools for diagnostic applications and
treatment of several chronic diseases. Hence, it is increasingly
important to investigate the rheological behaviour of physiological
fluids in microchannels. The main purpose of the present
experimental work is to investigate the flow of two different
physiological fluids frequently used in microfluidic devices.
The working fluids were physiological saline (PS) and dextran
40 (Dx40) containing about 6% of sheep red blood cells
(RBCs), respectively. The capillaries were placed horizontally
on a slide glass and the flow rate of the working fluids was kept
constant by using a syringe pump. By means of a camera the
images were taken and transferred to the computer to be analysed.
Generally, the results show that PS and Dx40 have different
flow behaviour due to the sedimentation of the RBCs.
Description
Keywords
Physiological fluids Red blood cells Microfluidic devices Sedimentation Microcirculation
Citation
Garcia, Valdemar; Correia, Teresa Montenegro; Dias, Ricardo P.; Lima, R. (2010). Flow of physiological fluids in microchannels: the sedimentation effect. In 6th World Congress of Biomechanics. Singapore. p.1071-1074. ISBN 978-3-642-14514-8