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Therapeutic uses and pharmacological properties of shallot (Allium ascalonicum): a systematic review

2022Artigo científico Acesso aberto
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dc.contributor.authorMoldovan, Cadmiel
dc.contributor.authorFrumuzachi, Oleg
dc.contributor.authorBabotă, Mihai
dc.contributor.authorBarros, Lillian
dc.contributor.authorMocan, Andrei
dc.contributor.authorCarradori, Simone
dc.contributor.authorCrisan, Gianina
dc.date.accessioned2022-07-29T14:50:03Z
dc.date.available2022-07-29T14:50:03Z
dc.date.issued2022
dc.description.abstractBackgroundShallot (Allium ascalonicum L.) is a traditional plant species used throughout the world both for culinary purposes and as a folk remedy. To date (i.e., April 2022), there is no report on the main pharmacological activities exerted by shallot preparations and/or extracts. Scope and ApproachThe aim of this study was to comprehensively review the pharmacological activities exerted by shallot, with rigorous inclusion and exclusion criteria based on the scientific rigor of studies. Prisma guidelines were followed to perform the literature search. Key Findings and ConclusionsThe literature search yielded 2,410 articles of which 116 passed the required rigorous criteria for inclusion in this review. The extracts exert a potent antioxidant activity both in vitro and in vivo, as well as a strong inhibitory capacity on various pathogens with relevant implications for public health. Moreover, shallot can be used as adjuvant therapy in cardiovascular diseases, diabetes, cancer prevention, and other non-communicable diseases associated with inflammatory and oxidative pathways. Future studies investigating the chemical composition of this species, as well as the molecular mechanisms involved in the empirically observed pharmacological actions are required.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMoldovan, Cadmiel; Frumuzachi, Oleg; Babotă, Mihai; Barros, Lillian; Mocan, Andrei; Carradori, Simone; Crisan, Gianina. (2022). Therapeutic uses and pharmacological properties of shallot (Allium ascalonicum): a systematic review. Frontiers in Nutrition. ISSN 2296-861X. 9, p. 1-34pt_PT
dc.identifier.issn2296-861X
dc.identifier.urihttp://hdl.handle.net/10198/25769
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherFrontierspt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectShallotpt_PT
dc.subjectAllium ascalonicum
dc.subjectAllium cepa var
dc.subjectAggregatum
dc.subjectPharmacological activity
dc.subjectTherapeutic use
dc.titleTherapeutic uses and pharmacological properties of shallot (Allium ascalonicum): a systematic reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleFrontiers in Nutritionpt_PT
person.familyNameBarros
person.givenNameLillian
person.identifier469085
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id35236343600
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication.latestForDiscovery3af07ffe-f914-48ba-a5d5-efcf70fdce01

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