Publicação
Competitive Adsorption of Phenolic Acids, Secoiridoids, and Flavonoids in Quercetin Molecularly Imprinted Polymers and Application for Fractionation of Olive Leaf Extracts
| dc.contributor.author | Almeida, Ayssata Patrícia da Costa Leocádia Vaz | |
| dc.contributor.author | Martins, Ana Filipa | |
| dc.contributor.author | Dias, Rolando | |
| dc.contributor.author | Costa, Mário Rui | |
| dc.date.accessioned | 2024-10-21T13:57:07Z | |
| dc.date.available | 2024-10-21T13:57:07Z | |
| dc.date.issued | 2024 | |
| dc.description.abstract | The competitive adsorption of phenolic acids, secoiridoids, and flavonoids in a molecularly imprinted polymer (MIP) functionalized with 4-vinylpiridine (4VP) moieties is analyzed here considering vanillic acid, oleuropein, and quercetin as reference molecules. Measured adsorption isotherms highlight a much stronger binding capacity of the quercetin-MIP particles toward quercetin as compared with vanillic acid and oleuropein. The acquired data were used to design and scale-up sorption/desorption processes aiming at the fractionation of olive leaf extracts. We show that a simple adsorption process, avoiding many pre-preparation steps, is possible when working at a high extract concentration due to the strong binding capacity of the MIP for flavonoids, even when using aqueous mixtures with a large alcoholic content. Solvent-gradient/temperature-swing desorption led to a sequence of fractions with enrichment of non-flavonoids at low alcoholic content while glycosylated flavonoids were enriched in fractions with 40% < alcohol content < 80%. Enrichment factors of 13 and 12 were measured for luteolin-7-O-glucoside and apigenin-7-O-glucoside, respectively. Flavonoid aglycones were enriched in fractions with alcohol content >80% (enrichment factors >20 for luteolin and quercetin). The findings reported here demonstrate the usefulness of the developed materials and sorption/desorption conditions for agricultural residue valorization and circular bioeconomy. | pt_PT |
| dc.description.sponsorship | The authors acknowledge the support through the OLEAF4VALUE project. This project had received funding from the Bio-Based Industries Joint Undertaking under the European Union's Horizon 2020 research and innovation programme under grant agreement no. 101023256. The authors also thank NATAC for providing the olive leaf extracts and the aid with the identification by LC-MS of compounds there contained. R.C.S.D. is grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 and UIDP/00690/2020) and SusTEC (LA/P/0007/2020). M.R.P.F.N.C. acknowledges the support by LA/P/0045/2020 (ALiCE), UIDB/50020/2020, and UIDP/50020/2020 (LSRE-LCM), funded by national funds through FCT/MCTES (PIDDAC). Ayssata Almeida acknowledges to FCT for the PhD scholarship PRT/BD/154653/2022 (CECA_IPB_1). | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Almeida, Ayssata; Martins, Cláudia; Dias, Rolando; Costa, Mário Rui P.F.N. (2024). Competitive Adsorption of Phenolic Acids, Secoiridoids, and Flavonoids in Quercetin Molecularly Imprinted Polymers and Application for Fractionation of Olive Leaf Extracts. ournal of Chemical & Engineering Data. ISSN 0021-9568. 69:10, p. 3629–3644 | pt_PT |
| dc.identifier.doi | 10.1021/acs.jced.3c00543 | pt_PT |
| dc.identifier.eissn | 1520-5134 | |
| dc.identifier.issn | 0021-9568 | |
| dc.identifier.uri | http://hdl.handle.net/10198/30477 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | American Chemical Society | pt_PT |
| dc.relation | Mountain Research Center | |
| dc.relation | Mountain Research Center | |
| dc.relation | Associate Laboratory for Sustainability and Tecnology in Mountain Regions | |
| dc.relation | ALICE - Associate Laboratory in Chemical Engineering | |
| dc.relation | Laboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials | |
| dc.relation | Laboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials | |
| dc.relation | Design and synthesis of natural-synthetic hybrid polymer particles for the valorization of bioactive compounds in olive leaf and olive oil production residues | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Ultrasound-assisted extraction | pt_PT |
| dc.subject | Selective recognition | pt_PT |
| dc.title | Competitive Adsorption of Phenolic Acids, Secoiridoids, and Flavonoids in Quercetin Molecularly Imprinted Polymers and Application for Fractionation of Olive Leaf Extracts | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardNumber | UIDB/00690/2020 | |
| oaire.awardNumber | UIDP/00690/2020 | |
| oaire.awardNumber | LA/P/0007/2020 | |
| oaire.awardNumber | LA/P/0045/2020 | |
| oaire.awardNumber | UIDB/50020/2020 | |
| oaire.awardNumber | UIDP/50020/2020 | |
| oaire.awardNumber | PRT/BD/154653/2022 | |
| oaire.awardTitle | Mountain Research Center | |
| oaire.awardTitle | Mountain Research Center | |
| oaire.awardTitle | Associate Laboratory for Sustainability and Tecnology in Mountain Regions | |
| oaire.awardTitle | ALICE - Associate Laboratory in Chemical Engineering | |
| oaire.awardTitle | Laboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials | |
| oaire.awardTitle | Laboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials | |
| oaire.awardTitle | Design and synthesis of natural-synthetic hybrid polymer particles for the valorization of bioactive compounds in olive leaf and olive oil production residues | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00690%2F2020/PT | |
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| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50020%2F2020/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//PRT%2FBD%2F154653%2F2022/PT | |
| oaire.citation.endPage | 3644 | pt_PT |
| oaire.citation.startPage | 3629 | pt_PT |
| oaire.citation.title | Journal of Chemical & Engineering Data | pt_PT |
| oaire.fundingStream | 6817 - DCRRNI ID | |
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| oaire.fundingStream | 6817 - DCRRNI ID | |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| person.familyName | Dias | |
| person.givenName | Rolando | |
| person.identifier.ciencia-id | 8417-4D84-973B | |
| person.identifier.orcid | 0000-0001-7369-382X | |
| person.identifier.rid | M-8552-2013 | |
| person.identifier.scopus-author-id | 7102885104 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
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| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
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| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
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