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Hypericum genus cosmeceutical application - a decade comprehensive review on its multifunctional biological properties

2021Artigo científico Acesso aberto
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dc.contributor.authorSilva, Ana Rita
dc.contributor.authorTaofiq, Oludemi
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2021-12-02T16:36:55Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2021-12-02T16:36:55Z
dc.date.issued2021
dc.description.abstractHypericum is a genus of flowering plants and presents a nearly worldwide distribution. The relevance of its species is mainly based on the occurrence of specialised secondary metabolites exhibiting a wide range of pharmaceutical and cosmeceutical properties. The most well-reported species in the last decade is H. perforatum, together with its exceptional polycyclic polyprenylated acylphloroglucinols metabolites. Several inhibitory enzyme properties such as anti-tyrosinase, anti-hyaluronidase, anti-collagenase, and anti-elastase, along with the relevant cosmeceutical anti-inflammatory and antimicrobial activities, have been reported in numerous biological studies concerning this genus. From 2010 to date were published more than 3000 articles; therefore, an updated summary of Hypericum species and their related cosmeceutical bioactive compounds is necessary. This detailed analysis will be mainly focused on cosmeceutical-related bioactivity, phytochemical composition, and the products and processes that have been developed using the generated knowledge. Despite all the progress made in recent years, which contributed to a state-of-the-art improvement, only a few studies regarding the genus have been dedicated to investigating the mechanisms of action and the safety (toxicology) of its bioactive compounds using well-validated methodologies. A strategic partnership between RD and vital cosmeceutical enterprises could be the requisite to promote the development of a higher number of efficient and marketable Hypericum-derived cosmeceutical products.en_EN
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES to CIMO (UIDB/00690/2020). L. Barros is also thankful to FCT through the institutional scientific employment program-for her contract. Ana Rita Silva is also grateful to FCT for her Doctoral Grant (SFRH/BD/145834/2019). Oludemi Taofiq is grateful to the European Regional Development Fund (ERDF) through the Regional Operational Program North 2020, within the scope of Project Mobilizador Norte-01- 0247-FEDER-024479: ValorNatural® for his contract.
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationSilva, Ana Rita; Taofiq, Oludemi; Ferreira, Isabel C.F.R.; Barros, Lillian (2021) - Hypericum genus cosmeceutical application - a decade comprehensive review on its multifunctional biological properties. Industrial Crops and Products. ISSN 0926-6690. 159, p. 1-en_EN
dc.identifier.doi10.1016/j.indcrop.2020.113053en_EN
dc.identifier.issn0926-6690
dc.identifier.urihttp://hdl.handle.net/10198/24447
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relationMountain Research Center - UIDB/00690/2020
dc.relationCytinus hypocistis L. L.: a case study for the development of an innovative, safe, and effective anti-photoaging cosmeceutical formulation
dc.subjectBioactive compoundsen_EN
dc.subjectBiological propertiesen_EN
dc.subjectCosmeceutical applicationen_EN
dc.subjectHypericum genusen_EN
dc.subjectHypericum perforatumen_EN
dc.titleHypericum genus cosmeceutical application - a decade comprehensive review on its multifunctional biological propertiesen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDB/00690/2020
oaire.awardNumberSFRH/BD/145834/2019
oaire.awardTitleMountain Research Center - UIDB/00690/2020
oaire.awardTitleCytinus hypocistis L. L.: a case study for the development of an innovative, safe, and effective anti-photoaging cosmeceutical formulation
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POR_NORTE/SFRH%2FBD%2F145834%2F2019/PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamPOR_NORTE
person.familyNameSilva
person.familyNameFerreira
person.familyNameBarros
person.givenNameAna Rita
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.identifierABD-5857-2020
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person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0001-5819-9065
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id35236343600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
relation.isAuthorOfPublication4b329c1a-e6c5-4e48-aac5-b19a6b91a279
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