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- Assessing the nutritional and functional properties of mushrooms from North-Eastern PortugalPublication . Martins, Joana; Garcia, Juliana; Gouvinhas, Irene; Pinto, Diana; Rodrigues, Francisca; Saavedra, Maria José; Alves, Maria JoséMushrooms are recognized as functional foods with noteworthy nutritional, culinary, and pharmacological properties, leading to their growing consumption. The present study aimed to compare the chemical composition and biological properties of six wild species harvested in north-eastern Portugal and two cultivated species (Lentinula edodes and Pleurotus citrinopileatus, purchased in Portuguese retail markets) to evaluate their potential as sources of nutrients and bioactive compounds. The results showed diverse macronutrient proximate profiles, characterized by high carbohydrate, dietary fibre, and protein, along with low-fat content and with moderate antioxidant activity. Notably, glucans were present in high amounts, with beta-glucans representing the major fraction. Despite species-specific variations, potassium and phosphorus were the predominant mineral elements. Additionally, lysine and arginine were the most abundant free amino acids in the samples. Overall, this manuscript provides a comprehensive insight into the chemical composition, bioactive properties, and nutritional potential of commercially available and wild mushrooms, supplying the first detailed glucan, mineral and antioxidant profile for five under-studied wild species from north-eastern Portugal.
- Plant-Derived Bioactive Compounds: One Health PerspectivePublication . Gonçalves, Ana Carolina Almeida ; Pinto, Ana R.; Cima, André; Olo-Fontinha, Eva; Martins, Joana; Garcia, Juliana; Lemos, André; Saavedra, Maria José; Pintado, Maria Manuela; Alves, Maria JoséThis review, within the One Health framework, compiles information on plant-derived bioactive compounds and emphasises their multifunctional role in improving environmental, animal, and human health. These compounds support sustainable health and ecological stability by influencing biological and environmental processes. Data from literature research are combined to explain the mechanisms and potential uses of different key bioactive compounds. Mechanistic insights focus on their capacity to regulate oxidative stress, inflammation, and microbial balance, linking these effects to therapeutic benefits in human health, enhanced animal productivity, and environmental sustainability. These compounds show antioxidant, anti-inflammatory, antimicrobial, and metabolic activities, helping prevent chronic diseases, strengthen immunity, and reduce reliance on antibiotics and pollution. Examples like quercetin, resveratrol, and curcumin demonstrate their roles in modulating inflammatory and metabolic pathways to foster sustainable health and ecological balance. Bioactive compounds are linked to the One Health strategy, providing benefits across biological systems. Nonetheless, challenges such as variability, bioavailability, and standardization remain. Future directions should aim to develop sustainable extraction and formulation methods, leverage omics technologies and artificial intelligence for discovery and characterization, and foster industry partnerships to validate these compounds and secure global regulatory approval.
