Percorrer por autor "Freitas, Filipa"
A mostrar 1 - 3 de 3
Resultados por página
Opções de ordenação
- Addressing the Challenges of Integrating Artificial Intelligence in Project ManagementPublication . Almeida, Pedro; Freitas, Filipa; Fernandes, Gabriela; Santos, José M.R.C.A.; Moniz, SamuelIn recent years, Artificial Intelligence (AI) has been transforming various fields, including Project Management (PM). While AI offers significant benefits to PM, its implementation also presents several challenges. This paper explores some of the main barriers faced by organizations when integrating AI into PM practice. Through a review of current literature, this study identifies major challenges, such as the creation of unemployment, the need for upskilled project managers, erosion capabilities of project managers, ethical issues, high initial investment, security and data privacy concerns, and data availability. By analyzing these challenges, this paper provides insights into strategic approaches for overcoming them, emphasizing the importance of change management strategies, investment in training, development of clear ethical regulations, and the highlighting the need for Project managers to develop a versatile skills set that balances technical proficiency with human-centric skills like empathy, adaptability, collaborative mindset, and emotional intelligence. These findings help to equip PM professionals with the necessary knowledge to navigate through the complexities of AI implementation effectively, while also guides scholars for future research on this emergent field.
- Development of high performance and facile to pack molecularly imprinted particles for aqueous applicationsPublication . Oliveira, Daniela; Freitas, Filipa; Kadhirvel, Porkodi; Dias, Rolando; Costa, Mário RuiDifferent kinds of molecularly imprinted particles were synthesized and compared, aiming at the development of materials combining high molecular recognition capabilities and facile use as column packing materials for chromatographic aqueous applications. Solution, inverse-suspension and precipitation polymerization were considered and two different model molecules (5-fluorouracil and caffeine) were used to highlight the effect of the interaction between the template molecule and the functional monomer on imprinting efficiency. Particles synthesized through the proposed inverse-suspension process exhibit facile use for packing columns, allow the stable running of chromatographic systems and present a high performance in drug uptake and release in aqueous media. Frontal analysis measurements highlight these key features of the synthesized particles. Drug sorption capabilities of 0.890 mol/g and 5.774 mol/g were measured for 5-fluorouracil and caffeine, respectively, using frontal analysis with eluents containing the target molecules at concentration 0.1 mM. Due to the lower amount of solvent required than with precipitation polymerization, the developed inverse-suspension process presents high synthesis yields, which can be exploited for the large-scale manufacture and commercialization of molecularly imprinted materials. The combined features of the particles makes possible their direct use in bioseparations or in the development of assays and pharmacokinetic studies concerning the presence of drugs in biological fluids.
- Development of tailored hydrogels using RAFT polymerization in continuous flow microreactorPublication . Machado, Carla; Oliveira, Tânia; Reitor, Patrícia; Oliveira, Daniela; Freitas, Filipa; Kadhirvel, Porkodi; Dias, Rolando; Costa, Mário RuiThis research is devoted to the development of tools aiding the production of smart hydrogels with tailored molecular architecture and properties. Molecular imprinting, RAFT polymerization and operation in continuous flow microreactor are individually considered and also simultaneously combined in order to try the synthesis of materials with improved performance.