Browsing by Author "Collazo, Nicolas"
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- Health promoting properties of bee royal jelly: Food of the queensPublication . Collazo, Nicolas; Carpena Rodríguez, María; Núñez Estévez, Bernabé; Otero, Paz; Simal-Gandara, Jesus; Prieto Lage, Miguel A.Royal jelly (RJ) demand is growing every year and so is the market for functional foods in general. RJ is formed by different substances, mainly carbohydrates, proteins, and lipids, but also vitamins, minerals, and phenolic or volatile compounds in lower proportion. Major royal jelly proteins (MRJP) are, together with 10†hydroxy†2†decenoic acid (10†HDA), key substances of RJ due to their different biological properties. In particular, 10†HDA is a unique substance in this product. RJ has been historically employed as health enhancer and is still very relevant in China due to the traditional medicine and the apitherapy. Nowadays, it is mainly consumed as a functional food or is found in supplements and other formulations for its health†beneficial properties. Within these properites, anti†lipidemic, antioxidant, antiproliferative, antimicrobial, neuroprotective, anti†inflammatory, immunomodulatory, antiaging, and estrogenic activities have been reported for RJ or its specific components. This manuscript is aimed at reviewing the current knowledge on RJ components, their assessment in terms of authenticity, their biological activities, and related health applications.
- Plant antioxidants from agricultural waste: synergistic potential with other biological properties and possible applicationsPublication . Carpena Rodríguez, María; García-Oliveira, Paula; González Pereira, Antía; Soria-Lopez, Anton; Chamorro Rivo, Franklin Noel; Collazo, Nicolas; Jarboui, Amira; Simal-Gandara, Jesus; Prieto Lage, Miguel A.The increasing world population entails a great necessity to produce large amounts of food, leading to an increase in organic waste. Unlike traditional agriculture, based on the circular sustainability, modern agriculture produces tons of residues, which are accumulated in landfills or, in some cases, burnt. Numerous studies have demonstrated that agricultural residues are rich in bioactive compounds, particu- larly phenolic compounds, with antioxidant properties. Antioxidant activity has been widely related with protective effects and prevention potential for different diseases. Also, the scavenging and protective effects of antioxidant compounds have shown a connection and synergistic effect with other biological properties, such as anti-inflammatory, anti-tumor, anti-aging, neuroprotective, cardio- protective, or antidiabetic. These compounds can be applied in several fields, including food, cosmetic, and pharmaceutical industry. This chapter will be focused on the interconnected bioactive properties and possible applications of plant-origin compounds with antioxidant potential to valorize different agricultural waste.
- Xanthophylls from the sea: Algae as source of bioactive carotenoidsPublication . González Pereira, Antía; Otero, Paz; Echave Álvarez, Javier; Carreira Casais, Anxo; Chamorro Rivo, Franklin Noel; Collazo, Nicolas; Jaboui, Amira; Lourenço-Lopes, Catarina; Simal-Gandara, Jesus; Prieto Lage, Miguel A.Algae are considered pigment-producing organisms. The function of these compounds in algae is to carry out photosynthesis. They have a great variety of pigments, which can be classified into three large groups: chlorophylls, carotenoids, and phycobilins. Within the carotenoids are xanthophylls. Xanthophylls (fucoxanthin, astaxanthin, lutein, zeaxanthin, and β-cryptoxanthin) are a type of carotenoids with anti-tumor and anti-inflammatory activities, due to their chemical structure rich in double bonds that provides them with antioxidant properties. In this context, xanthophylls can protect other molecules from oxidative stress by turning off singlet oxygen damage through various mechanisms. Based on clinical studies, this review shows the available information concerning the bioactivity and biological effects of the main xanthophylls present in algae. In addition, the algae with the highest production rate of the different compounds of interest were studied. It was observed that fucoxanthin is obtained mainly from the brown seaweeds Laminaria japonica, Undaria pinnatifida, Hizikia fusiformis, Sargassum spp., and Fucus spp. The main sources of astaxanthin are the microalgae Haematococcus pluvialis, Chlorella zofingiensis, and Chlorococcum sp. Lutein and zeaxanthin are mainly found in algal species such as Scenedesmus spp., Chlorella spp., Rhodophyta spp., or Spirulina spp. However, the extraction and purification processes of xanthophylls from algae need to be standardized to facilitate their commercialization. Finally, we assessed factors that determine the bioavailability and bioaccesibility of these molecules. We also suggested techniques that increase xanthophyll's bioavailability.