Percorrer por autor "Capristano, Jeovana"
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- Exploring cardiovascular risk and plasma ghrelin levels in older adults: a preliminary studyPublication . Alves, Sara Elisa Brás; Capristano, Jeovana; Sá, Leandro Moreira de; Mendes, Eugénia; Fernandes, Hélder; Vaz, Josiana A.Cardiovascular diseases are a leading cause of illness and mortality worldwide, with ageing as a key risk factor. As people age, heightened inflammation, oxidative stress, and endothelial dysfunction increase their cardiovascular disease risk. Ghrelin, known as "the hunger hormone," is essential for energy regulation and metabolism. It offers cardiovascular benefits by promoting vasodilation and enhancing endothelial function. With anti-inflammatory and antioxidative properties, ghrelin aids vascular health, making it particularly significant for ageing populations where these processes are often disrupted. Imbalanced ghrelin levels may increase the risk of atherosclerosis and other cardiovascular complications. Understanding these variations in plasma ghrelin levels can offer insights into individual susceptibility to cardiovascular disease and highlight the hormone's role in metabolic and cardiovascular health. This preliminary study aimed to evaluate cardiovascular risk and plasma ghrelin levels in a community of 16 older adults aged 60 or above
- Sleep quality and hormonal levels of ghrelin and leptin in the elderly: a cross-sectional studyPublication . Alves, Sara Elisa Brás; Capristano, Jeovana; Sá, Leandro Moreira de; Mendes, Eugénia; Fernandes, Hélder; Vaz, Josiana A.The increase in life expectancy prompts a critical examination of the quality of aging in contemporary societies. Ageing causes alterations in the circadian sleep-wake cycle, which are closely linked to cellular senescence. Research indicates that insufficient sleep can accelerate inflammation and oxidative stress, highlighting the importance of good sleep hygiene for overall health and reducing the effects of ageing. Sleep quality is closely connected to hormonal balance, particularly ghrelin, leptin, melatonin, and serotonin. These hormones play significant roles in regulating appetite, metabolism, sleep patterns, and emotional well-being. This study aimed to evaluate sleep quality in a group of elderly individuals (N=25) and its relationship with serum levels of ghrelin and leptin. Sleep quality was assessed using the Portuguese version of the Pittsburgh Sleep Quality Index. Blood collection for laboratory tests was performed according to WHO guidelines