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Publication
Thermal infrared image processing to assess heat generated by magnetic nanoparticles for hyperthermia applications
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Advisor(s)
Abstract(s)
Magnetic fluid hyperthermia (MFH) is considered a promising therapeutic
technique for the treatment of cancer cells, in which magnetic nanoparticles
(MNPs) with superparamagnetic behavior generate mild-temperatures
under an AC magnetic field to selectively destroy the abnormal cancer cells, in
detriment of the healthy ones. However, the poor heating efficiency of most NMPs
and the imprecise experimental determination of the temperature field during the
treatment, are two of the majors drawbacks for its clinical advance. Thus, in this
work, different MNPs were developed and tested under an AC magnetic field
(~1.10 kA/m and 200 kHz), and the heat generated by them was assessed by an
infrared camera. The resulting thermal images were processed in MATLAB after
the thermographic calibration of the infrared camera. The results show the potential
to use this thermal technique for the improvement and advance of MFH as a
clinical therapy.
Description
Keywords
Thermal imaging Image calibration Image processing
Citation
Rodrigues, Raquel O.; Gomes, Helder; Lima, R.; Silva, Adrián M.T.; Rodrigues, Pedro J.S.; Tavares, Pedro B.; Tavares, João Manuel R.S. (2015). Thermal infrared image processing to assess heat generated by magnetic nanoparticles for hyperthermia applications. In 11th International Symposium on Visual Computing (ISVC). Las vegas. p. 25-34.