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Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study

2004Journal article Open access
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dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorEstevinho, Leticia M.
dc.contributor.authorQueiroz, Maria João R.P.
dc.date.accessioned2008-09-12T13:33:00Z
dc.date.available2008-09-12T13:33:00Z
dc.date.issued2004
dc.description.abstractGram positive (Bacillus cereus, B. subtilis), Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria, and Candida albicans as a representative of fungi were used for screening the in vitro antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[ b]thiophene series bearing different substituents, synthesized by us using the palladium-catalyzed C–N coupling methodology. The minimal inhibitory concentration (MIC) and structure–activity relationships (SARs) were evaluated.en
dc.identifier.citationFerreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Leticia M.; Queiroz, Maria João R.P. (2004). Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation study. Bioorganic & Medicinal Chemistry Letters. ISSN 0960-894X. 14:23, p. 5831-5833en
dc.identifier.doi10.1016/j.bmcl.2004.09.038
dc.identifier.issn0960-894X
dc.identifier.urihttp://hdl.handle.net/10198/821
dc.language.isoengen
dc.publisherElsevieren
dc.subjectDiarylaminesen
dc.subjectAntimicrobial activityen
dc.subjectSARen
dc.subjectBenzothiophenesen
dc.titleScreening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: A structure-activity evaluation studyen
dc.typejournal article
dspace.entity.typePublication
person.familyNameFerreira
person.familyNameCalhelha
person.familyNameEstevinho
person.givenNameIsabel C.F.R.
person.givenNameRicardo C.
person.givenNameLetícia M.
person.identifier144781
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.ciencia-idBA14-09D6-A406
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0002-9249-1948
person.identifier.ridE-8500-2013
person.identifier.ridJ-2172-2014
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id6506577664
rcaap.rightsopenAccess
rcaap.typearticleen
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relation.isAuthorOfPublication.latestForDiscovery4a1d5ba2-1854-4ca5-89a4-73f35e964df9

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