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Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw

2015Journal article Open access
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dc.contributor.authorPereira, Carla
dc.contributor.authorBarros, Lillian
dc.contributor.authorAlves, Maria José
dc.contributor.authorPereira, Liliana
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2015-11-25T15:52:37Z
dc.date.available2015-11-25T15:52:37Z
dc.date.issued2015
dc.description.abstractThree different formulations (infusion, pills and syrup) of Cochlospermum angolensis were characterized by HPLC-DAD-ESI/MS regarding phenolic composition, and evaluated by their in vitro antimicrobial activity against clinical isolates of multiresistant bacteria. Infusion and pills showed the highest variety of phenolic compounds, with eleven molecules identified. Protocatechuic acid was only present in infusions, being the most abundant compound, while (epi)gallocatechin-O-gallate was the main molecule identified in pills and eucaglobulin/globulusin in syrup. Infusion revealed antimicrobial activity against all the studied bacteria with the exception of Proteus mirabilis whereas the pills revealed activity in Escherichia coli spectrum extended producer of β-lactamases and methicillin-resistant Staphylococcus aureus. In the syrup there was no antimicrobial activity detected, which is in agreement with its low concentrations of phenolic compounds. None of the formulations inhibited P. mirabilis. Considering the obtained results, C. angolensis infusion can be considered a good source of phenolic compounds as well as a good antimicrobial agent.pt_PT
dc.description.sponsorshipThe authors are grateful to Foundation for Science and Technology (FCT, Portugal) for financial support to the research center CIMO (strategic project PEst-OE/AGR/UI0690/2014) and L. Barros researcher contract under “Programa Compromisso com Ciência – 2008”.pt_PT
dc.identifier10.1016/j.indcrop.2015.05.056
dc.identifier.citationPereira, Carla; Barros, Lillian; Alves, Maria José; Pereira, Liliana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2015). Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw. Industrial Crops and Products. ISSN 0926-6690. 74, p. 412-416pt_PT
dc.identifier.doi10.1016/j.indcrop.2015.05.056pt_PT
dc.identifier.issn0926-6690
dc.identifier.urihttp://hdl.handle.net/10198/12421
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCochlospermum angolensispt_PT
dc.subjectInfusion/pills/syruppt_PT
dc.subjectPhenolic compoundspt_PT
dc.subjectAntimicrobial activitypt_PT
dc.subjectClinical isolatespt_PT
dc.titlePhenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welwpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/PEst-OE%2FAGR%2FUI0690%2F2014/PT
oaire.citation.endPage416pt_PT
oaire.citation.startPage412pt_PT
oaire.citation.titleIndustrial Crops and Productspt_PT
oaire.citation.volume74pt_PT
oaire.fundingStream5876
person.familyNamePereira
person.familyNameBarros
person.familyNameAlves
person.familyNamePereira
person.familyNameFerreira
person.givenNameCarla
person.givenNameLillian
person.givenNameMaria José
person.givenNameLiliana
person.givenNameIsabel C.F.R.
person.identifier1415151
person.identifier469085
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person.identifier.ciencia-idD618-B3A9-D312
person.identifier.ciencia-idEF14-9663-7872
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0003-0093-771X
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0001-8506-4393
person.identifier.orcid0000-0002-0211-6205
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridK-1629-2016
person.identifier.ridJ-3600-2013
person.identifier.ridM-6624-2016
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id55627876424
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id16400584800
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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