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QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition

2011Journal article Restricted access
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dc.contributor.authorFroufe, Hugo J.C.
dc.contributor.authorAbreu, Rui M.V.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2011-11-04T11:48:30Z
dc.date.available2011-11-04T11:48:30Z
dc.date.issued2011
dc.description.abstractWild mushrooms have become attractive as a source of physiologically beneficial compounds including antioxidants such as phenolic compounds and tocopherols. The concentrations of antioxidant compounds (phenolics and α-tocopherol) and EC50 values of antioxidant activity (concentration required to achieve 50% of radical scavenging activity and lipid peroxidation inhibition, or 0.5 of absorbance in reducing power) were analyzed by partial least square (PLS) regression analysis. Three QCAR (Quantitative Composition-Activity Relationship) models were constructed and their robustness and predictability were verified by internal and external cross-validation methods. Antioxidant activity correlated well with phenolics and -tocopherol contents, the major antioxidants in wild mushrooms. The models proved to be useful tools in the prediction of mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition.por
dc.identifier.citationFroufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R. (2011). QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. Chemometrics and Intelligent Laboratory Systems. ISSN 0169-7439. 109:2, p. 192-196por
dc.identifier.doi10.1016/j.chemolab.2011.09.004
dc.identifier.issn0169-7439
dc.identifier.urihttp://hdl.handle.net/10198/6271
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relationPortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines
dc.subjectWild mushroomspor
dc.subjectPhenolicspor
dc.subjectAlpha-tocopherolpor
dc.subjectAntioxidant activitypor
dc.subjectQCARpor
dc.subjectPLSpor
dc.titleQCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibitionpor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitlePortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FAGR-ALI%2F110062%2F2009/PT
oaire.citation.endPage196por
oaire.citation.issue109(2)por
oaire.citation.startPage192por
oaire.citation.titleChemometrics and Intelligent Laboratory Systemspor
oaire.fundingStream5876-PPCDTI
person.familyNameAbreu
person.familyNameFerreira
person.givenNameRui M.V.
person.givenNameIsabel C.F.R.
person.identifier144781
person.identifier.ciencia-id0F19-0DE2-12A2
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-7745-8015
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id7003290613
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicationcadb03a4-5e60-4745-b35f-fc3a97c071bc
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication.latestForDiscoverybd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isProjectOfPublication59db4b60-8cc2-4f07-a25a-8cfe78f2778f
relation.isProjectOfPublication.latestForDiscovery59db4b60-8cc2-4f07-a25a-8cfe78f2778f

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