Repository logo
 
Publication

Relevance of horse chestnut (Aesculus hippocastanum L.) saponins in health and cosmetics

2021Conference object Open access
Simple item page
dc.contributor.authorAlbiston, Carly
dc.contributor.authorPinela, José
dc.contributor.authorAñibarro-Ortega, Mikel
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.date.accessioned2022-01-21T15:22:26Z
dc.date.available2022-01-21T15:22:26Z
dc.date.issued2021
dc.description.abstractSaponins are steroidal glycosides or polycyclic terpenes resulting from the secondary plant metabolism and have many beneficial characteristics and applications. They can be used to fight and cure many diseases and health issues, as well as in cosmetics and as natural alternatives for food preservation and packaging [1,2]. Due to the finite resources our planet can provide and the increasing potential for saponins in various sectors, it is necessary to find alternative sources of these pharmacologically active high-added values compounds. This study aims to provide an overview of the bioactive properties of saponins that can be found in Aesculus hippocastanum L. The saponins found in this plant have a trisaccharide chain at C3 of the aglycone and a ꞵ-glucopyranosyl unit attached at C4 of the glucuronic acid. Aescin (Figure 1) is the main active component and responsible for most of its medicinal properties [2,3]. These saponins have already been described as more antioxidants than vitamin E and capable of protecting cells from free radicals and reactive species [2,4]. These compounds shown positive effects on venous insufficiency and associated conditions, reduce capillary fragility, and help prevent the leakage of fluids into surrounding tissues, thus presenting beneficial effects on human skin [2]. Due to these properties, A. hippocastanum saponins can be used in cosmetic formulations with anti-aging capacity [2]. The bark of this plant has also been used to treat dermatitis, while the leaves and seeds are used due to their anti-inflammatory effects [3]. ꞵ-Aescin (the main active compound of aescin) is a natural inhibitor of leukemic cell proliferation and may be useful for new anti-leukemic drugs [5]. ꞵ-Aescin has also been reported to be effective for the treatment of colon cancer [4]. Therefore, given the high added-value of aescin, it would be interesting to develop an extraction method that maximizes the recovery of these compounds from this plant in a sustainable way to promote resource use efficiency.pt_PT
dc.description.sponsorshipTo FCT for financial support through national funds FCT/MCTES to CIMO (UIDB/00690/2020); for the M. Añibarro-Ortega PhD grant (2020.06297.BD) and the contracts of J. Pinela (CEECIND/01011/2018) and L. Barros through the individual and institutional scientific employment program-contract, respectively; to C. Albiston grant through CIMO funds; and to the FEDER-Interreg España-Portugal programme for financial support through the Project TRANSCoLAB 0612_TRANS_CO_LAB_2_P and to ERDF through the Regional Operational Program North 2020, within the scope of Project GreenHealth - Norte-01-0145-FEDER-000042.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAlbiston, Carly; Pinela, José; Añibarro-Ortega, Mikel; Ferreira, Isabel C.F.R.; Barros, Lillian (2021). Relevance of horse chestnut (Aesculus hippocastanum L.) saponins in health and cosmetics. In 1st Natural products application: health, cosmetic and food: book of abstracts. Bragança: Instituto Politécnico. ISBN 978-972-745-286-6pt_PT
dc.identifier.isbn978-972-745-286-6
dc.identifier.urihttp://hdl.handle.net/10198/24842
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationMountain Research Center
dc.relationNot Available
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAesculus hippocastanum Lpt_PT
dc.titleRelevance of horse chestnut (Aesculus hippocastanum L.) saponins in health and cosmeticspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardTitleNot Available
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/CEEC IND 2018/CEECIND%2F01011%2F2018%2FCP1578%2FCT0002/PT
oaire.citation.conferencePlaceBragança, Portugalpt_PT
oaire.citation.titleNatural Products Application: Health, Cosmetic and Foodpt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamCEEC IND 2018
person.familyNamePinela
person.familyNameAñibarro-Ortega
person.familyNameFerreira
person.familyNameBarros
person.givenNameJosé
person.givenNameMikel
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.identifier144781
person.identifier469085
person.identifier.ciencia-id771C-2B43-B108
person.identifier.ciencia-idC61D-DD88-73C7
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0001-7523-1637
person.identifier.orcid0000-0002-2835-5079
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridB-4466-2014
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id54392272800
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id35236343600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication706cd9ff-065b-4c98-98a7-5c0a9e45adc4
relation.isAuthorOfPublication7235cb7a-09a1-453b-b39b-52989046fab6
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication.latestForDiscovery7235cb7a-09a1-453b-b39b-52989046fab6
relation.isProjectOfPublication29718e93-4989-42bb-bcbc-4daff3870b25
relation.isProjectOfPublicationec142c57-5163-4512-9a14-7319866da393
relation.isProjectOfPublication.latestForDiscovery29718e93-4989-42bb-bcbc-4daff3870b25

Files

Collections

CIMO - Resumos em Proceedings Não Indexados à WoS/Scopus