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Pharmacological potential of green tomato glycoalcaloids: an overview

2021Conference poster Open access
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dc.contributor.authorPinela, José
dc.contributor.authorAñibarro-Ortega, Mikel
dc.contributor.authorOliveira, Beatriz
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.date.accessioned2022-01-21T15:41:03Z
dc.date.available2022-01-21T15:41:03Z
dc.date.issued2021
dc.description.abstractGlycoalkaloids are characteristic secondary metabolites in plants of the Solanaceae family. Although perceived as potentially toxic, these compounds display different bioactivities and pharmacological effects. The glycoalkaloids esculeoside A and tomatine (which comprises a junction of α-tomatine and dehydrotomatine) can be found in tomato plants. Structurally, dehydrotomatine differs from α-tomatine by having a double bond in the steroidal B ring of the aglycone; but both glycoalkaloids have the same tetrasaccharide (lycotetraose) side chain. Therefore, while α-tomatine has lycotetraose bonded to the aglycone tomatidine, dehydrotomatine has the side chain attached to the aglycone tomatidenol. Up to 500 mg/kg FW of tomatine can be found in unripe (green) tomatoes, levels that decrease with ripening (approximately 5 mg/kg FW in ripe red tomatoes) [1]. On the other hand, the content of esculeoside A, which is stored in ripe red tomatoes, is comparable to or higher than that of lycopene [2]. Thus, the levels of esculeoside A increase as the fruit matures, contrary to that observed for tomatine.pt_PT
dc.description.sponsorshipTo FCT for financial support through national funds FCT/MCTES to CIMO (UIDB/00690/2020); for the M. Añibarro-Ortega grant (2020.06297.BD) and the J. Pinela contract (CEECIND/01011/2018) through the individual scientific employment program-contract; and to ERDF through the Regional Operational Program North 2020, within the scope of the Project GreenHealth - Norte-01-0145-FEDER-000042..pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPinela, José; Añibarro-Ortega, Mikel; Oliveira, Beatriz; Ferreira, Isabel C.F.R.; Barros, Lillian (2021). Pharmacological potential of green tomato glycoalcaloids: an overview. In 2021 #RSCPoster Twitter Conferencept_PT
dc.identifier.urihttp://hdl.handle.net/10198/24846
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationMountain Research Center
dc.relationNot Available
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectSolanaceae familypt_PT
dc.titlePharmacological potential of green tomato glycoalcaloids: an overviewpt_PT
dc.typeconference poster
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardTitleNot Available
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/CEEC IND 2018/CEECIND%2F01011%2F2018%2FCP1578%2FCT0002/PT
oaire.citation.title#RSC Poster Twitter Conferencept_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamCEEC IND 2018
person.familyNamePinela
person.familyNameAñibarro-Ortega
person.familyNameFerreira
person.familyNameBarros
person.givenNameJosé
person.givenNameMikel
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.identifier144781
person.identifier469085
person.identifier.ciencia-id771C-2B43-B108
person.identifier.ciencia-idC61D-DD88-73C7
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0001-7523-1637
person.identifier.orcid0000-0002-2835-5079
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridB-4466-2014
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id54392272800
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id35236343600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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