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Advisor(s)
Abstract(s)
A new computer simulation using a particle method was proposed to analyze the microscopic
behavior of blood flow. A simulation region, including plasma, red blood cells (RBCs) and platelets, was
modeled by an assembly of discrete particles. The proposed method was applied to the motions and deformations
of a single RBC and multiple RBCs, and the thrombogenesis caused by platelet aggregation. It is
expected that, combined with a sophisticated large-scale computational technique, the simulation method will
be useful for understanding the overall properties of blood flow from blood cellular level (microscopic) to the
resulting rheological properties of blood as a mass (macroscopic).
Description
Keywords
Computational biomechanics Blood flow Red blood cell Platelet
Citation
Tsubota, K.; Wada, S.; Kamada, H.; Kitagawa, Y.; Lima, R.; Yamaguchi, T. (2006). A particle method for blood flow simulation: application to flowing red blood cells and platelets. Journal of the Earth Simulator. ISSN 1349-2667. 5, p.2-7