Logo do repositório
 
Publicação

Optimization of heat-assisted extraction of bioactive compounds from Thymus vulgaris L.

2021Documento de conferência Acesso aberto
Ver registo simples
dc.contributor.authorAraújo, Catarina
dc.contributor.authorSprea, Rafael M.
dc.contributor.authorPereira, Eliana
dc.contributor.authorFinimundy, Tiane C.
dc.contributor.authorCarocho, Márcio
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorAmaral, Joana S.
dc.contributor.authorCaleja, Cristina
dc.contributor.authorBarros, Lillian
dc.date.accessioned2022-01-21T12:48:13Z
dc.date.available2022-01-21T12:48:13Z
dc.date.issued2021
dc.description.abstractAromatic and medicinal plants have been used worldwide since ancient times, for being attributed to them capable bioactive properties associated mainly with the relevant composition of several phytochemicals, including polyphenols [1]. Thymus vulgaris L. is a species described as a potential source of natural ingredients with application in the food industry, but also in the cosmetic and therapeutic industry due to its antibacterial, antifungal, and anti-inflammatory effects [2]. In this sense, the present study aimed to optimize the extraction of phenolic compounds from T. vulgaris through the heat-assisted technique (HAE), aiming at its potential for exploration in industry. For this propose, three independent variables, time (t, minutes), temperature (T, ºC) and solvent (S, % of ethanol) were combined in a five-level central composite rotatable design coupled with the response surface methodology (RSM). The extraction yield and the content of phenolic compounds identified by HPLC-DAD-ESI/MS were the experimental responses used in the optimization. The polynomial models were successfully fitted to the experimental data and used to determine the optimal HAE conditions. Nineteen phenolic compounds were identified, nine of which were identified as phenolic acids (mainly caffeic acid derivatives), ten as flavonoids: flavan-3-ols (catechin derivatives), flavones (quercetin derivatives), flavonols (apigenin and luteolin derivatives) and flavanones (eriodictyol derivatives). The conditions that appear to be optimal for the extraction of phenolic compounds and that allowed the experimental validation of the predictive model are 3% solution ethanol: water (v/v) for 89 minutes at a temperature of 98º C. The optimization of extraction is important from an industrial point of view, as it allows obtaining extracts with a high content of bioactive compounds from natural matrices, in this case, T. vulgaris leaves. Considering that the phenolic composition appears in literature as a direct influence on bioactive properties, optimization processes allows a better exploitation of extracts, ensuring the greatest economic reduction for industries.pt_PT
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES to CIMO (UIDB/00690/2020); national funding by FCT, P.I., through the institutional and individual scientific employment program-contract for L. Barros and M. Carocho (CEECIND/00831/2018) contracts; to the research contract of C. Caleja (Project HealthyPETFOOD, POCI-01-0247-FEDER-047073) and E. Pereira (Mobilizador Norte-01-0247-FEDER-024479: ValorNatural®); to FEDER-Interreg España-Portugal program for financial support through the project TRANSCoLAB 0612_TRANS_CO_LAB_2_P, to FEDER through the Regional Operational Program North 2020, under the Project GreenHealth (Norte-01-0145-FEDER-000042); and through the Incentive System to Research and Technological development, within the Portugal2020 Competitiveness and Internationalization Operational Program, under the Project BIOMA (POCI-01-0247-FEDER-046112).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAraújo, Catarina; Sprea, Rafael M.; Pereira, Eliana; Finimundy, Tiane C.; Carocho, Márcio; Ferreira, Isabel C.F.R.; Amaral, Joana S.; Caleja, Cristina; Barros, Lillian (2021). Optimization of heat-assisted extraction of bioactive compounds from Thymus vulgaris L.. In 5th International Symposium on Phytochemicals in Medicine and Food. Nanchangpt_PT
dc.identifier.urihttp://hdl.handle.net/10198/24827
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherUniversidade de Vigopt_PT
dc.relationUIDB/00690/2020)pt_PT
dc.relationCEECIND/00831/2018pt_PT
dc.relationPOCI-01-0247-FEDER-047073pt_PT
dc.relationNorte-01-0247-FEDER-024479pt_PT
dc.relationNorte-01-0145-FEDER-000042pt_PT
dc.relationPOCI-01-0247-FEDER-046112pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectThymus vulgaris L.pt_PT
dc.titleOptimization of heat-assisted extraction of bioactive compounds from Thymus vulgaris L.pt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceNanchangpt_PT
oaire.citation.endPage286pt_PT
oaire.citation.startPage286pt_PT
oaire.citation.title5th International Symposium on Phytochemicals in Medicine and Foodpt_PT
person.familyNameSprea
person.familyNamePereira
person.familyNameFinimundy
person.familyNameCarocho
person.familyNameFerreira
person.familyNameAmaral
person.familyNameCaleja
person.familyNameBarros
person.givenNameRafael M.
person.givenNameEliana
person.givenNameTiane C.
person.givenNameMárcio
person.givenNameIsabel C.F.R.
person.givenNameJoana S.
person.givenNameCristina
person.givenNameLillian
person.identifierawbWiiMAAAAJ&hl
person.identifier144781
person.identifier469085
person.identifier.ciencia-id001F-273E-3A67
person.identifier.ciencia-idBE17-462D-9A75
person.identifier.ciencia-id2F18-67B1-776A
person.identifier.ciencia-id5614-005B-5CF1
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id5319-7DE8-BEDA
person.identifier.ciencia-idE218-8DD3-4959
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0003-2854-6745
person.identifier.orcid0000-0003-3516-0795
person.identifier.orcid0000-0002-8978-4547
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-3648-7303
person.identifier.orcid0000-0002-5769-8484
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridQ-8017-2018
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id55938912300
person.identifier.scopus-author-id52463229800
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id36514202500
person.identifier.scopus-author-id35236343600
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication7779265b-4054-4822-9a2a-03b1482c81e0
relation.isAuthorOfPublicationdda60cdc-0a2a-4c10-863e-eaef1e6f1fb9
relation.isAuthorOfPublication4f8767d4-4e62-4550-9b35-740cb2f672da
relation.isAuthorOfPublication46b39e1f-2674-4be1-a96a-c2e5792e6979
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication42be2cf4-adc4-4e7f-ac60-7aab515b38cd
relation.isAuthorOfPublication5ef2706d-073c-4c23-9e45-498ac244118c
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication.latestForDiscovery4f8767d4-4e62-4550-9b35-740cb2f672da

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
FA - 5ISPMF_SPREA.pdf
Tamanho:
1 MB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

CIMO - Resumos em Proceedings Não Indexados à WoS/Scopus