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Bioinformatics: new tools and applications in life science and personalized medicine

dc.contributor.authorBranco, Iuliia
dc.contributor.authorChoupina, Altino
dc.date.accessioned2021-02-15T15:42:22Z
dc.date.available2021-02-15T15:42:22Z
dc.date.issued2021
dc.description.abstractWhile we have a basic understanding of the functioning of the gene when coding sequences of specific proteins, we feel the lack of information on the role that DNA has on specific diseases or functions of thousands of proteins that are produced. Bioinformatics combines the methods used in the collection, storage, identification, analysis, and correlation of this huge and complex information. All this work produces an “ocean” of information that can only be “sailed” with the help of computerized methods. The goal is to provide scientists with the right means to explain normal biological processes, dysfunctions of these processes which give rise to disease, and approaches that allow the discovery of new medical cures. Recently, sequencing platforms, a large scale of genomes and transcriptomes, have created new challenges not only to the genomics but especially for bioinformatics. The intent of this article is to compile a list of tools and information resources used by scientists to treat information from the massive sequencing of recent platforms to new generations and the applications of this information in different areas of life sciences including medicine.pt_PT
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2019).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBranco, Iuliia; Choupina, Altino (2021). Bioinformatics: new tools and applications in life science and personalized medicine. Applied Microbiology and Biotechnology. ISSN 0175-7598. 105:3, p. 937-951pt_PT
dc.identifier.doi10.1007/s00253-020-11056-2pt_PT
dc.identifier.eissn1432-0614
dc.identifier.issn0175-7598
dc.identifier.urihttp://hdl.handle.net/10198/23294
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Naturept_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectSequencingpt_PT
dc.subjectBioinformaticspt_PT
dc.subjectToolspt_PT
dc.subjectApplicationspt_PT
dc.subjectLife sciencept_PT
dc.subjectPersonalized medicinept_PT
dc.titleBioinformatics: new tools and applications in life science and personalized medicinept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSpringer Netherlandspt_PT
oaire.citation.endPage951pt_PT
oaire.citation.startPage937pt_PT
oaire.citation.titleApplied Microbiology and Biotechnologypt_PT
person.familyNameChoupina
person.givenNameAltino
person.identifier587972
person.identifier.ciencia-id1A14-77FC-9656
person.identifier.orcid0000-0002-3956-9398
person.identifier.ridL-5382-2014
person.identifier.scopus-author-id14051602500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication314b895b-a5e2-4a92-9bc6-dd708c819be4
relation.isAuthorOfPublication.latestForDiscovery314b895b-a5e2-4a92-9bc6-dd708c819be4

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