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History of secondary metabolites: from ancient myths to modern scientific validation

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dc.contributor.authorPedrosa, Mariana C.
dc.contributor.authorLima, Laíres
dc.contributor.authorAloso-Esteban, José Ignacio
dc.contributor.authorRoriz, Custódio Lobo
dc.contributor.authorBarros, Lillian
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorCarocho, Márcio
dc.date.accessioned2024-01-03T10:09:57Z
dc.date.available2024-01-03T10:09:57Z
dc.date.issued2023
dc.description.abstractThe study of primary plant metabolism has been the main focus of scientists for several years, seconding research related to the secondary metabolism. Nowadays, with the better understanding of the processes and products involved in primary metabolism, the focus has switched to the expansion of knowledge involving secondary metabolism. Initially, plants were the focus of secondary metabolite studies due to their ease of acquisition and availability, reasons for being a term coined by plant physiologists. Only in the twentieth century has the secondary metabolites from microorganisms began to be recognized and investigated due to the value that these metabolites could bring to science. Not by chance, it was in the twentieth century that the era of antibiotics began. In this chapter, a voyage through the centuries is proposed, focused on secondary metabolism and metabolites, highlighting how they shifted from disregarded molecules to the powerhouses of bioactivity for modern science.pt_PT
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES to the CIMO (UIDB/00690/ 2020). M.C. Pedrosa thanks FCT for her PhD grant (2021.04531.BD), M. Carocho thanks FCT for their individual scientific contract (CEEC-IND/00831/2018). C.L. Roriz thanks the European Regional Development Fund (ERDF) through the Competitiveness and Internationalization Operational Program for financial support to the project 100% Figo (POCI-01-0247-FEDER-064977). L. Barros thanks FCT through the institutional scientific employment contract.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPedrosa, Mariana C.; Lima, Laíres; Aloso-Esteban, José Ignacio; Roriz, Custódio Lobo; Barros, Lillian; Ferreira, Isabel C.F.R.; Carocho, Márcio (2023). History of secondary metabolites: from ancient myths to modern scientific validation. Natural Secondary Metabolites: From Nature, Through Science, to Industry. Cham: Springer Nature. p. 3-18. ISBN 978-3-031-18586-1pt_PT
dc.identifier.doi10.1007/978-3-031-18587-8_1pt_PT
dc.identifier.isbn978-3-031-18586-1
dc.identifier.isbn978-3-031-18587-8 (eBook)
dc.identifier.urihttp://hdl.handle.net/10198/29028
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Naturept_PT
dc.relationMountain Research Center
dc.relationSUSPLA: Development of PLA Biofilms from Food Waste, Incorporated with Bioactive Preserving Molecules
dc.relationNot Available
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectGenept_PT
dc.subjectLignificationpt_PT
dc.subject4-coumarate-coa ligasept_PT
dc.titleHistory of secondary metabolites: from ancient myths to modern scientific validationpt_PT
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardTitleSUSPLA: Development of PLA Biofilms from Food Waste, Incorporated with Bioactive Preserving Molecules
oaire.awardTitleNot Available
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//2021.04531.BD/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/CEEC IND 2018/CEECIND%2F00831%2F2018%2FCP1578%2FCT0001/PT
oaire.citation.endPage18pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage3pt_PT
oaire.citation.titleNatural Secondary Metabolites: From Nature, Through Science, to Industrypt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamCEEC IND 2018
person.familyNamePedrosa
person.familyNameLima
person.familyNameRoriz
person.familyNameBarros
person.familyNameFerreira
person.familyNameCarocho
person.givenNameMariana C.
person.givenNameLaíres
person.givenNameCustódio Lobo
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.givenNameMárcio
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person.identifier.orcid0000-0002-2057-0639
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person.identifier.orcid0000-0002-4021-1078
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-8978-4547
person.identifier.ridJ-3600-2013
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project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
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