Mass spectrometry-based approaches to assess the botanical authenticity of dietary supplements

Grazina, Liliana; Mafra, Isabel; Monaci, Linda; Amaral, Joana S.

Publication

Mass spectrometry-based approaches to assess the botanical authenticity of dietary supplements

2023Journal article

dc.contributor.author	Grazina, Liliana
dc.contributor.author	Mafra, Isabel
dc.contributor.author	Monaci, Linda
dc.contributor.author	Amaral, Joana S.
dc.date.accessioned	2018-03-09T16:01:37Z
dc.date.available	2018-03-09T16:01:37Z
dc.date.issued	2023
dc.description.abstract	Dietary supplements are legally considered foods despite frequently including medicinal plants as ingredients. Currently, the consumption of herbal dietary supplements, also known as plant food supplements (PFS), is increasing worldwide and some raw botanicals, highly demanded due to their popularity, extensive use, and/or well-established pharmacological effects, have been attaining high prices in the international markets. Therefore, botanical adulteration for profit increase can occur along the whole PFS industry chain, from raw botanicals to plant extracts, until final PFS. Besides the substitution of high-value species, unintentional mislabeling can happen in morphologically similar species. Both cases represent a health risk for consumers, prompting the development of numerous works to access botanical adulterations in PFS. Among different approaches proposed for this purpose, mass spectrometry (MS)-based techniques have often been reported as the most promising, particularly when hyphenated with chromatographic techniques. Thus, this review aims at describing an overview of the developments in this field, focusing on the applications of MS-based techniques to targeted and untargeted analysis to detect botanical adulterations in plant materials, extracts, and PFS.	pt_PT
dc.description.sponsorship	The authors acknowledge the support of FCT (Fundação para a Ciência e Tecnologia) through the project “POIROT: novel methods and approaches for detecting the illegal addition of Pharmaceutical drugs and bOtanIcal adulteRatiOn in planT food supplements” (PTDC/SAU-PUB/3803/2021); the strategic funding of CIMO (UIDB/00690/2020\|UIDP/00690/2020), SusTEC (LA/P/0007/2020), and REQUIMTE (UIDB/50006/2020\|UIDP/50006/2020) from FCT/MCTES (PIDDAC); and the European Union (EU) through European Regional Development Fund with the project Healthy&ValorFood (FEDER funds through NORTE-01- 0145-FEDER-000052). L. Grazina is grateful to FCT grants (SFRH/BD/132462/2017 and COVID/BD/152444/2022) financed by POPH-QREN (subsidized by FSE and MCTES). I. Mafra thanks FCT for funding through the Individual Call to Scientific Employment Stimulus (2021.03670.CEECIND/CP1662/CT0011). This work was also supported by the project SYSTEMIC under the ERA-NET ERA-HDHL (no. 696295).
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Grazina, Liliana; Mafra, Isabel; Monaci, Linda; Amaral, Joana S. (2023). Mass spectrometry-based approaches to assess the botanical authenticity of dietary supplements. Comprehensive Reviews in Food Science and Food Safety. ISSN 1541-4337. 22:5, p. 3870-3909	pt_PT
dc.identifier.doi	10.1111/1541-4337.13222
dc.identifier.issn	1541-4337
dc.identifier.uri	http://hdl.handle.net/10198/16247
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Wiley
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Adulteration	pt_PT
dc.subject	Botanical origin	pt_PT
dc.subject	Plant food supplements	pt_PT
dc.subject	Targeted MS	pt_PT
dc.subject	Untargeted MS
dc.title	Mass spectrometry-based approaches to assess the botanical authenticity of dietary supplements	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.title	Comprehensive Reviews in Food Science and Food Safety	pt_PT
person.familyName	Soares Amaral
person.givenName	Joana Andrêa
person.identifier.ciencia-id	5319-7DE8-BEDA
person.identifier.orcid	0000-0002-3648-7303
rcaap.rights	openAccess	pt_PT
rcaap.type	article	pt_PT
relation.isAuthorOfPublication	42be2cf4-adc4-4e7f-ac60-7aab515b38cd
relation.isAuthorOfPublication.latestForDiscovery	42be2cf4-adc4-4e7f-ac60-7aab515b38cd