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Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods

2023Journal article Open access
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dc.contributor.authorNicolescu, Alexandru
dc.contributor.authorBabotă, Mihai
dc.contributor.authorBarros, Lillian
dc.contributor.authorLucini, Luigi
dc.contributor.authorTanase, Corneliu
dc.contributor.authorMocan, Andrei
dc.contributor.authorBunea, Claudiu I.
dc.contributor.authorCrisan, Gianina
dc.date.accessioned2014-11-19T09:03:24Z
dc.date.available2014-11-19T09:03:24Z
dc.date.issued2023
dc.description.abstractNutraceuticals and functional foods are composed of especially complex matrices, with polyphenols, carotenoids, minerals, and vitamins, among others, being the main classes of phytochemicals involved in their bioactivities. Despite their wide use, further investigations are needed to certify the proper release of these phytochemicals into the gastrointestinal medium, where the bioaccessibility assay is one of the most frequently used method. The aim of this review was to gather and describe different methods that can be used to assess the bioaccessibility of nutraceuticals and functional foods, along with the most important factors that can impact this process. The link between simulated digestion testing of phytochemicals and their in vitro bioactivity is also discussed, with a special focus on the potential of developing nutraceuticals and functional foods from simple plant materials. The bioactive potential of certain classes of phytochemicals from nutraceuticals and functional foods is susceptible to different variations during the bioaccessibility assessment, with different factors contributing to this variability, namely the chemical composition and the nature of the matrix. Regardless of the high number of studies, the current methodology fails to assume correlations between bioaccessibility and bioactivity, and the findings of this review indicate a necessity for updated and standardized protocols.por
dc.description.sponsorshipThis work was supported by a grant of the Romanian Ministry of Education and Research, CNCS–UEFISCDI, project number PN-III-P2-2.1-PED-2019–5360.
dc.identifier.citationNicolescu, Alexandru; Babotă, Mihai; Barros, Lillian; Lucini, Luigi; Tanase, Corneliu; Mocan, Andrei; Bunea, Claudiu I.; Crisan, Gianina (2023). Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods. Frontiers in Nutrition. ISSN 2296-861X. 10, p. 1-18por
dc.identifier.doi10.3389/fnut.2023.1184535
dc.identifier.issn2296-861X
dc.identifier.urihttp://hdl.handle.net/10198/11398
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherFrontierspor
dc.subjectBioaccessibility
dc.subjectNutraceuticals
dc.subjectFunctional foods
dc.subjectPhytonutrients
dc.subjectPolyphenols
dc.subjectCarotenoids
dc.titleBioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foodspor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleFrontiers in Nutritionpor
person.familyNameBarros
person.givenNameLillian
person.identifier469085
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id35236343600
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication.latestForDiscovery3af07ffe-f914-48ba-a5d5-efcf70fdce01

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