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Orientador(es)
Resumo(s)
The grafting of functional brushes on the surface of molecularly imprinted polymer (MIP). particles hás
been explored in the last few years to synthesize materiais combining high molecular recognition
capabilities and stimulation triggered by changes in the surrounding environment [1, 2]. In the present
work, MIP particles for 5-fluorouracil (a drug used in câncer treatment) were produced by precipitation
polymerization in acetonitrile, using either MAA or HEMA as imprinting fünctional monomers, and m
the presence of different kinds of RAFT agents. In a second step, taking advantage of the RAFT groups
present in the surface of the particles, different kinds of fiinctional polymer brushes were grafted on the
MIPs considering a "grafting from" process in the presence of a RAFT agent.
Descrição
Palavras-chave
Molecular imprinting RAFT polymerization Surface grafting
Contexto Educativo
Citação
Oliveira, Daniela; Dias, Rolando; Costa, Mário (2016). Grafting of functional brushes on the surface of 5-Fluorouracil molecularly imprinted polymer particles through RAFT polymerization. In 12th International Workshop on Polymer Reaction Engineering. University of Hamburg, Germany