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Optimization of the extraction of phenolic compounds from Ganoderma lucidum

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dc.contributor.authorTaofiq, Oludemi
dc.contributor.authorBarros, Lillian
dc.contributor.authorPrieto Lage, Miguel A.
dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorBarreiro, M.F.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2018-05-16T10:36:57Z
dc.date.available2018-05-16T10:36:57Z
dc.date.issued2018
dc.description.abstractGanoderma lucidum (Curtis) P. Karst, a rich source of several bioactive compounds, has been utilized for its medicinal and nutraceutical purposes since earliest history. Among its bioactive constituents, the phenolic content has been widely reported to be responsible for some its bioactive properties. Recent trends in bioactive compounds’ recovery have been focused on finding the best techniques that maximally extract valuable compounds from natural matrices. This study is aimed at optimizing the extraction of phenolic compounds (Ph) from G. lucidum using conventional techniques such as Soxhlet extraction (SE), heat assisted extraction (HAE) and comparing with ultrasound assisted extraction (UAE), considered a more sustainable method. The SE technique was optimized by applying 7 cycles while to effectively carry out the optimization of HAE and UAE, response surface methodology (RSM) was applied using a circumscribed central composite design with three independent variables (time, ethanol content, temperature or ultrasonic power). The extraction yield and total Ph were maximized and the optimal conditions were determined. For the SE technique, a positive linear dependency was achieved for the extraction yield, while for the Ph content expressed in terms of mg equiv. gallic acid (EGA) per g dw (dry weight), a significantly increase was observed up to the 5th cycle before a gradual decrease. The conditions that maximize the responses (extraction yield and total phenolics) were: 78.9 min, 90.0 °C and 62.5 % ethanol and 40 min, 100.0 W and 89.5% ethanol for HAE and UAE, respectively. The latter was the most effective, capable of achieving 4.9 ± 0.6 % extraction yield and 106.6 ± 16.2 mg EGA/g dw. The extraction process optimization proved to be a viable option for obtaining phenolic rich extracts from G. lucidum that can be used as bio-based ingredients.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTaofiq, Oludemi; Barros, Lillian; Prieto, Miguel A.; Heleno, Sandrina A.; Barreiro, M.F.; Ferreira, Isabel C.F.R. (2018). Optimization of the extraction of phenolic compounds from Ganoderma lucidum. In 9es Journées Scientifiques Internationales sur la Valorisation des Bioressources. Monastir, Tunisiapt_PT
dc.identifier.urihttp://hdl.handle.net/10198/17641
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleOptimization of the extraction of phenolic compounds from Ganoderma lucidumpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceMonastir, Tunisiapt_PT
oaire.citation.title9es Journées Scientifiques Internationales sur la Valorisation des Bioressourcespt_PT
person.familyNameBarros
person.familyNamePrieto
person.familyNameHeleno
person.familyNameBarreiro
person.familyNameFerreira
person.givenNameLillian
person.givenNameMiguel A.
person.givenNameSandrina A.
person.givenNameFilomena
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifier107688
person.identifier144781
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id221E-1E00-AB74
person.identifier.ciencia-id8B18-3095-6FC9
person.identifier.ciencia-id3418-47D5-5746
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-3513-0054
person.identifier.orcid0000-0001-7224-1098
person.identifier.orcid0000-0002-6844-333X
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridG-4516-2011
person.identifier.ridL-5951-2014
person.identifier.ridL-9802-2014
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id35937495700
person.identifier.scopus-author-id30067731800
person.identifier.scopus-author-id57188719717
person.identifier.scopus-author-id36868826600
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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relation.isAuthorOfPublication13260615-fd28-4b8b-9dd4-8a8466007579
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