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Melissa officinalis L. decoctions as functional beverages: a bioactive approach and chemical characterization

dc.contributor.authorCarocho, Márcio
dc.contributor.authorBarros, Lillian
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorĆirić, Ana
dc.contributor.authorSoković, Marina
dc.contributor.authorSantos-Buelga, Celestino
dc.contributor.authorMorales, Patricia
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2015-11-26T11:11:23Z
dc.date.available2015-11-26T11:11:23Z
dc.date.issued2015
dc.description.abstractLemon balm (Melissa officinalis L.) is a member of the Lamiaceae family with a long story of human consumption. It has been consumed for decades, directly in food and as a decoction or an infusion for its medicinal purposes. In this manuscript, a detailed chemical characterization of the decoction of this plant is described, encompassing antimicrobial, antioxidant and antitumor activities. Rosmarinic acid and lithospermic acid A were the most abundant phenolic compounds. Quinic acid, fructose, glucose and γ-tocopherol were the most abundant within their groups of molecules. M. officinalis decoctions were active against a wide range of microorganisms, Pseudomonas aeruginosa and Salmonella typhimurium, and Penicillium funiculosum being the most sensitive bacteria and fungi, respectively. The growth inhibition of different human tumor cell lines (mainly MCF-7 and HepG2) was also observed, as also high free radical scavenging activity and reducing power. This manuscript highlights some beneficial effects of these functional beverages.pt_PT
dc.description.sponsorshipThe authors are grateful to the company Mais Ervas, Lda. for providing the M. officinalis samples. The authors also acknowledge PRODER project No. 46577-Plant Lact., the Foundation for Science and Technology (FTC, Portugal) for financial support to CIMO (Pest-OE/AGR/UI0690/2011) and L. Barros, and the Serbian Ministry of Education, Science and Technological Development for the Grant No 173032.pt_PT
dc.identifier10.1039/c5fo00309a
dc.identifier.citationCarocho, Márcio; Barros, Lillian; Calhelha, Ricardo C.; Ćirić, Ana; Soković, Marina; Santos-Buelga, Celestino; Morales, Patricia; Ferreira, Isabel C.F.R. (2015). Melissa officinalis L. decoctions as functional beverages: a bioactive approach and chemical characterization. Food & Function. ISSN 2042-6496. 6:7, p. 2240-2248pt_PT
dc.identifier.doi10.1039/c5fo00309apt_PT
dc.identifier.issn2042-6496
dc.identifier.urihttp://hdl.handle.net/10198/12430
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationPRODER 46577 - Plant Lactpt_PT
dc.relationStrategic Project - UI 690 - 2011-2012
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleMelissa officinalis L. decoctions as functional beverages: a bioactive approach and chemical characterizationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.citation.endPage2248pt_PT
oaire.citation.startPage2240pt_PT
oaire.citation.titleFood & Functionpt_PT
oaire.citation.volume6pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameCarocho
person.familyNameBarros
person.familyNameCalhelha
person.familyNameFerreira
person.givenNameMárcio
person.givenNameLillian
person.givenNameRicardo C.
person.givenNameIsabel C.F.R.
person.identifierawbWiiMAAAAJ&hl
person.identifier469085
person.identifier144781
person.identifier.ciencia-id5614-005B-5CF1
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-8978-4547
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridJ-2172-2014
person.identifier.ridE-8500-2013
person.identifier.scopus-author-id52463229800
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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