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Antioxidants in wild mushrooms

dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.contributor.authorAbreu, Rui M.V.
dc.date.accessioned2010-11-19T12:04:35Z
dc.date.available2010-11-19T12:04:35Z
dc.date.issued2009
dc.description.abstractMaintenance of equilibrium between free radical production and antioxidant defences (enzymatic and non enzymatic) is an essential condition for normal organism functioning. When this equilibrium has a tendency for the production of free radicals we say that the organism is in oxidative stress. In this situation, excess free radicals may damage cellular lipids, proteins and DNA, affecting normal function and leading to various diseases. In aerobic organisms, the free radicals are constantly produced during the normal cellular metabolism, mainly in the form of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS). Exposition of the organism to free radicals has led to the development of endogenous defence mechanisms to eliminate them. These defences were the response of evolution to the inevitability of ROS production in aerobic conditions. Natural products with antioxidant activity may help the endogenous defence system. In this perspective the antioxidants present in the diet assume a major importance as possible protector agents reducing oxidative damage. Particularly, the antioxidant properties of wild mushrooms have been extensively studied by our research group and by others, and many antioxidant compounds extracted from these sources have been identified, such as phenolic compounds, tocopherols, ascorbic acid, and carotenoids. We will review the compounds identified so far in mushrooms, as well as the mechanism of action involved in their antioxidant properties. Wild mushrooms might be used directly in diet and promote health, taking advantage of the additive and synergistic effects of all the bioactive compounds present.por
dc.identifier.citationFerreira, Isabel CFR; Barros, Lillian; Abreu, Rui M.V. (2009). Antioxidants in wild mushrooms. Current Medicinal Chemistry. ISSN 0929-8673. 16:12. p. 1543-1560por
dc.identifier.doi10.2174/092986709787909587
dc.identifier.issn0929-8673
dc.identifier.urihttp://hdl.handle.net/10198/2855
dc.language.isoengpor
dc.publisherBentham Science Publishers Ltd.por
dc.titleAntioxidants in wild mushroomspor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1560por
oaire.citation.startPage1543por
oaire.citation.titleCurrent Medicinal Chemistrypor
person.familyNameFerreira
person.familyNameBarros
person.familyNameAbreu
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.givenNameRui M.V.
person.identifier144781
person.identifier469085
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id9616-35CB-D001
person.identifier.ciencia-id0F19-0DE2-12A2
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-7745-8015
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id35236343600
person.identifier.scopus-author-id7003290613
rcaap.rightsopenAccesspor
rcaap.typearticlepor
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relation.isAuthorOfPublication.latestForDiscoverybd0d1537-2e03-41fb-b27a-140af9c35db8

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