Publication
Fish protein hydrolysates: bioactive properties, encapsulation and new technologies for enhancing peptides bioavailability
| dc.contributor.author | Moreira, Thaysa Fernandes Moya | |
| dc.contributor.author | Gonçalves, Odinei Hess | |
| dc.contributor.author | Leimann, Fernanda Vitória | |
| dc.contributor.author | Ribeiro, Ricardo Pereira | |
| dc.date.accessioned | 2024-02-20T11:46:40Z | |
| dc.date.available | 2024-02-20T11:46:40Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | Fish protein hydrolysates (FPHs) can be obtained from substrates such as fish muscle, skin, and wastes and assign value to these fish by-products. Proteolytic enzymes catalyze the hydrolysis of these fish substrates' peptide bonds resulting in smaller peptides that present several bioactive properties. Hydrolysates' bioactive properties are a function of the fish species used as the substrate, the enzyme selectivity or specificity, pH and temperature applied in the reaction, etc. Furthermore, many pre-treatment methods are being applied to fish protein substrates to improve their enzyme susceptibility and increase the number of smaller bioactive peptides. This review addresses the production of FPHs and the main bioactive properties evaluated recently in the literature and emphasizes the substrate treatments by high-pressure processing, microwave, ultrasound, and thermal treatments to achieve better bioactivity making essential amino acids more available in peptides. The bioactive properties most found in FPHs were antioxidants, antimicrobials, anticancer, and antihypertensive. These bioactivities may vary depending on the conditions of hydrolysis, fish species, and fractionation and isolation of specific peptides.New technologies for the treatment of by-products can reduce process losses and achieve better results by cleavage of proteins. Conversely, encapsulation and film utilization can improve bioactivity, bioavailability, and controlled release when applied to foods, resulting in improved health. | pt_PT |
| dc.description.sponsorship | The study is funded by the CNPq (Chamada Universal-MCTI/ CNPq No. 28/2018, Process 421541/2018-0) and Fundação Araucária (convênio 039/2019) for financial support. This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Moreira, Thaysa Fernandes Moya; Gonçalves, Odinei Hess; Leimann, Fernanda Vitória; Ribeiro, Ricardo Pereira (2023). Fish protein hydrolysates: bioactive properties, encapsulation and new technologies for enhancing peptides bioavailability. Current Pharmaceutical Design. ISSN 1381-6128. 29:11, p. 824-836 | pt_PT |
| dc.identifier.doi | 10.2174/1381612829666230110141811 | pt_PT |
| dc.identifier.eissn | 1873-4286 | |
| dc.identifier.issn | 1381-6128 | |
| dc.identifier.uri | http://hdl.handle.net/10198/29552 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Bentham Science | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Protein hydrolysates | pt_PT |
| dc.subject | Bioactive compounds | pt_PT |
| dc.subject | Bioactive peptides | pt_PT |
| dc.subject | Hydrophobic amino acids | pt_PT |
| dc.subject | Encapsulation | pt_PT |
| dc.subject | New technologies | pt_PT |
| dc.title | Fish protein hydrolysates: bioactive properties, encapsulation and new technologies for enhancing peptides bioavailability | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 836 | pt_PT |
| oaire.citation.issue | 11 | pt_PT |
| oaire.citation.startPage | 824 | pt_PT |
| oaire.citation.title | Current Pharmaceutical Design | pt_PT |
| oaire.citation.volume | 29 | pt_PT |
| person.familyName | Gonçalves | |
| person.familyName | Leimann | |
| person.givenName | Odinei Hess | |
| person.givenName | Fernanda Vitória | |
| person.identifier.ciencia-id | 8F10-A04D-FC0D | |
| person.identifier.orcid | 0000-0002-9528-8187 | |
| person.identifier.orcid | 0000-0001-6230-9597 | |
| person.identifier.scopus-author-id | 9335958400 | |
| rcaap.rights | restrictedAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 84c8eea0-77bb-4c18-b9d8-46f865980706 | |
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| relation.isAuthorOfPublication.latestForDiscovery | 84c8eea0-77bb-4c18-b9d8-46f865980706 |