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Synthesis of acetylated glucuronide derivatives of p-hydroxybenzoic and cinnamic acids, two compounds commonly found in wild mushrooms

2013Conference object Open access
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dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorMartins, Anabela
dc.contributor.authorEsteves, Ana P.
dc.contributor.authorQueiroz, Maria João R.P.
dc.date.accessioned2014-03-11T12:10:56Z
dc.date.available2014-03-11T12:10:56Z
dc.date.issued2013
dc.description.abstractDietary phenolic compounds are widely considered to contribute to health benefits in humans. However, little is known about their bioactive forms in vivo and the mechanisms by which they may contribute toward disease prevention. Moreover, many studies on the biological effects of phenolic compounds have ignored the question of their achievable concentrations in the circulation after ingestion as well as their metabolism [1]. Wild mushrooms are extensively studied due to their medicinal properties which have been related to the presence of bioactive molecules such as phenolic compounds. p-Hydroxibenzoic acid is among the most abundant phenolic acids found in wild mushrooms, as well as cinnamic acid [2]. The present work aims at contributing to the knowledge of the mechanisms involved in the healthpromoting properties of phenolic acids and precursors, usually present in mushrooms. Herein, we describe the synthesis of acetylated glucuronide derivatives of p-hydroxybenzoic and cinnamic acids, as protected glucuronide metabolites (Scheme).por
dc.description.sponsorshipFCT-Portugal for financial support to the Portuguese NMR network and to FCT and FEDER-COMPETE/QREN/EU for the financial support through the research project (PTDC/AGRALI/110062/2009), research centres (PEst-C/QUI/UI0686/2011 and PEst-OE/AGR/UI0690/2011) and through the PhD grant attributed to S.A.H. (SFRH/BD/70304/2010).por
dc.identifier.citationHeleno, Sandrina A.; Ferreira, Isabel C.F.R.; Martins, Anabela; Esteves, Ana P.; Queiroz, Maria João R. P. (2013). Synthesis of acetylated glucuronide derivatives of p-hydroxybenzoic and cinnamic acids, two compounds commonly found in wild mushrooms. In In 1st International Symposium on Profiling. Almada. ISBN 978-989-98415-5-0por
dc.identifier.isbn978-989-98415-5-0
dc.identifier.urihttp://hdl.handle.net/10198/9357
dc.language.isoengpor
dc.peerreviewedyespor
dc.relationPortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines
dc.relationStrategic Project - UI 686 - 2011-2012
dc.relationStrategic Project - UI 690 - 2011-2012
dc.relationIMPORTANT HUMAN METABOLITES OF PHENOLIC ACIDS FROM DIET WITH WILD EDIBLE MUSHROOMS: CHEMICAL SYNTHESIS AND STUDIES OF THEIR ANTIOXIDANT AND ANTITUMOR PROPERTIES
dc.titleSynthesis of acetylated glucuronide derivatives of p-hydroxybenzoic and cinnamic acids, two compounds commonly found in wild mushroomspor
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitlePortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines
oaire.awardTitleStrategic Project - UI 686 - 2011-2012
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardTitleIMPORTANT HUMAN METABOLITES OF PHENOLIC ACIDS FROM DIET WITH WILD EDIBLE MUSHROOMS: CHEMICAL SYNTHESIS AND STUDIES OF THEIR ANTIOXIDANT AND ANTITUMOR PROPERTIES
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FAGR-ALI%2F110062%2F2009/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6820 - DCRRNI ID/PEst-C%2FQUI%2FUI0686%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F70304%2F2010/PT
oaire.citation.conferencePlaceCaparica – Portugalpor
oaire.citation.title1st International Symposium on Profilingpor
oaire.fundingStream5876-PPCDTI
oaire.fundingStream6820 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameHeleno
person.familyNameFerreira
person.familyNameMartins
person.givenNameSandrina A.
person.givenNameIsabel C.F.R.
person.givenNameAnabela
person.identifier144781
person.identifier.ciencia-id8B18-3095-6FC9
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id7B18-A810-6B93
person.identifier.orcid0000-0001-7224-1098
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0001-6218-4413
person.identifier.ridL-5951-2014
person.identifier.ridE-8500-2013
person.identifier.ridG-5488-2013
person.identifier.scopus-author-id30067731800
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id7203013518
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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