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Micro-flow visualization of in vitro blood through a microchannel with a bifurcation and confluence

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dc.contributor.authorCidre, Diana
dc.contributor.authorLima, Rui A.
dc.contributor.authorFernandes, Carla S.
dc.contributor.authorDias, Ricardo P.
dc.contributor.authorIshikawa, Takuji
dc.contributor.authorImai, Yohsuke
dc.contributor.authorYamaguchi, Takami
dc.date.accessioned2011-05-30T09:19:31Z
dc.date.available2011-05-30T09:19:31Z
dc.date.issued2010
dc.description.abstractMicro-visualization techniques have been used to investigate the in vitro blood flow through straight glass capillaries. Although the glass microchannels present certain similarities to in vivo microcirculation, it is also clear that these kind of in vitro experiments differ from microvessels in several respects, such as: elasticity of microvessels, effect of the endothelial surface layer and microvascular networks composed with short irregular vessel segments which are linked by numerous bifurcations and convergences. Thus it was not surprising that several studies on blood flow in glass microtubes and in microvessels have yielded conflicting results with respect to blood viscosity and flow resistance. The main purpose of this work is to improve our understanding about the effect of a bifurcation and convergence on the rheological properties of in vitro blood. The microchannel containing a bifurcation and confluence will be fabricated in PDMS by using a soft lithography technique. The flow behaviour of both pure water (PW) and dextran 40 (Dx40) containing about 14% (14Hct) of human red blood cells (RBCs) will be investigated by means of a confocal micro-PTV system. Additionally, the experimental measurements obtained with PW will be also compared numerically by using the commercial finite element software package POLYFLOW®.por
dc.identifier.citationCidre, D.; Lima, R.; Fernandes, Carla S.; Dias, Ricardo P.; Ishikawa, T.; Imai, Y.; Yamaguchi, T. (2010). Micro-flow visualization of in vitro blood through a microchannel with a bifurcation and confluence. In 6th World Congress of Biomechanics. Singapure.por
dc.identifier.urihttp://hdl.handle.net/10198/4684
dc.language.isoengpor
dc.subjectBlood flowpor
dc.subjectBifurcationspor
dc.titleMicro-flow visualization of in vitro blood through a microchannel with a bifurcation and confluencepor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceSingapurepor
oaire.citation.title6th World Congress of Biomechanicspor
person.familyNameLima
person.familyNameFernandes
person.familyNameDias
person.givenNameRui A.
person.givenNameCarla S.
person.givenNameRicardo P.
person.identifier.ciencia-idEE12-C3FB-349D
person.identifier.ciencia-idF319-3D67-9DB7
person.identifier.orcid0000-0003-3428-637X
person.identifier.orcid0000-0002-3138-7493
person.identifier.orcid0000-0003-1503-998X
person.identifier.ridH-5157-2016
person.identifier.ridA-4269-2015
person.identifier.scopus-author-id18437397800
person.identifier.scopus-author-id8253740700
person.identifier.scopus-author-id7102885151
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication7b50c499-8095-4f4f-8b1b-fa7388e4ff62
relation.isAuthorOfPublication8f9cf139-cfef-4025-ba87-56425618bc6e
relation.isAuthorOfPublication5e7df3f1-9852-4d4b-8d5a-4e69eb79b164
relation.isAuthorOfPublication.latestForDiscovery7b50c499-8095-4f4f-8b1b-fa7388e4ff62

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