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Detailed phytochemical characterization and bioactive properties of: Myrtus nivelii Batt & Trab

dc.contributor.authorRached, Wahiba
dc.contributor.authorBennaceur, Malika
dc.contributor.authorBarros, Lillian
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorAlves, Maria José
dc.contributor.authorCarvalho, Ana Maria
dc.contributor.authorMarouf, Abderrazak
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2018-01-25T10:00:00Z
dc.date.accessioned2018-01-30T11:51:27Z
dc.date.available2018-01-25T10:00:00Z
dc.date.available2018-01-30T11:51:27Z
dc.date.issued2017
dc.description.abstractThe endemic Algerian myrtle, Myrtus nivelii Batt & Trab., was evaluated for its bioactive properties, such as antioxidant, anti-inflammatory, cytotoxic and antibacterial activities, and correlated with the individual phenolic compounds identified in its crude aqueous extract and subsequent organic fractions (ethyl acetate and butanol). Flavonols, such as myricetin, kaempferol and quercetin glycoside derivatives, were the major phenolic compounds found, along with the presence of ellagitannins. The ethyl acetate fraction contained the highest amount of phenolic compounds, followed by the butanol fraction and, finally, the crude aqueous extract. In general, all samples exhibited an excellent bioactivity, namely the ethyl acetate fraction that presented strong antioxidant activity, when compared to the standard trolox, strong cytotoxicity and antibacterial activity, especially against MRSA and MSSA. The present study revealed that the ethyl acetate fraction of M. nivelii could be used as a source of bioactive compounds in the food and pharmaceutical industries.pt_PT
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2013), L. Barros contract and S. Heleno (SFRH/BPD/101413/2014) grant. We greatly acknowledge the MESRS of Algeria for the financial support that allowed us to complete the internship period at the IPB in the PNE program. The authors are also grateful to the Interreg España-Portugal for financial support through the project 0377_Iberphenol_6_E).
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRached, Wahiba; Bennaceur, Malika; Barros, Lillian; Calhelha, Ricardo C.; Heleno, Sandrina; Alves, Maria José; Carvalho, Ana Maria; Marouf, Abderrazak; Ferreira, Isabel C.F.R. (2017). Detailed phytochemical characterization and bioactive properties of: Myrtus nivelii Batt & Trab. Food and Function. ISSN 2042-6496. 8, p. 3111-3119en_EN
dc.identifier.doi10.1039/c7fo00744bpt_PT
dc.identifier.issn2042-6496
dc.identifier.urihttp://hdl.handle.net/10198/15256
dc.language.isoeng
dc.peerreviewedyespt_PT
dc.relationObtaining of mycosterols to develop new functionalized foods: extraction, refinement, stabilization and incorporation into dairy products
dc.titleDetailed phytochemical characterization and bioactive properties of: Myrtus nivelii Batt & Traben_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleObtaining of mycosterols to develop new functionalized foods: extraction, refinement, stabilization and incorporation into dairy products
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F101413%2F2014/PT
oaire.fundingStream5876
person.familyNameBarros
person.familyNameCalhelha
person.familyNameHeleno
person.familyNameAlves
person.familyNameCarvalho
person.familyNameFerreira
person.givenNameLillian
person.givenNameRicardo C.
person.givenNameSandrina A.
person.givenNameMaria José
person.givenNameAna Maria
person.givenNameIsabel C.F.R.
person.identifier469085
person.identifierID G-7399-2011
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person.identifier.ciencia-id9616-35CB-D001
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person.identifier.ciencia-idD618-B3A9-D312
person.identifier.ciencia-idD31A-35AF-E2A9
person.identifier.ciencia-id9418-CF95-9919
person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0001-7224-1098
person.identifier.orcid0000-0001-8506-4393
person.identifier.orcid0000-0001-5508-5935
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
person.identifier.ridJ-2172-2014
person.identifier.ridL-5951-2014
person.identifier.ridM-6624-2016
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person.identifier.scopus-author-id35236343600
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person.identifier.scopus-author-id20336503900
person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticlept_PT
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