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Areca catechu - from farm to food and biomedical applications

2020Journal article Restricted access
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dc.contributor.authorSalehi, Bahare
dc.contributor.authorKonovalov, Dmitry A.
dc.contributor.authorFru, Pascaline
dc.contributor.authorKapewangolo, Petrina
dc.contributor.authorPeron, Gregorio
dc.contributor.authorKsenija, Mileski S.
dc.contributor.authorCardoso, Susana M.
dc.contributor.authorPereira, Olívia R.
dc.contributor.authorNigam, Manisha
dc.contributor.authorNicola, Silvana
dc.contributor.authorPignata, Giuseppe
dc.contributor.authorRapposelli, Simona
dc.contributor.authorSestito, Simona
dc.contributor.authorKumar, Nanjangud V. Anil
dc.contributor.authorCádiz‐Gurrea, María Luz
dc.contributor.authorSegura‐Carretero, Antonio
dc.contributor.authorMishra, Abhay P.
dc.contributor.authorSharifi‐Rad, Mehdi
dc.contributor.authorCho, William C.
dc.contributor.authorTaheri, Yasaman
dc.contributor.authorSetzer, William N.
dc.contributor.authorSharifi-Rad, Javad
dc.date.accessioned2020-05-15T10:26:38Z
dc.date.available2020-05-15T10:26:38Z
dc.date.issued2020
dc.description.abstractThe family Arecaceae includes 181 genera and 2,600 species with a high diversity in physical characteristics. Areca plants, commonly palms, which are able to grow in nearly every type of habitat, prefer tropical and subtropical climates. The most studied species Areca catechu L. contains phytochemicals as phenolics and alkaloids with biological properties. The phenolics are mainly distributed in roots followed by fresh unripe fruits, leaves, spikes, and veins, while the contents of alkaloids are in the order of roots, fresh unripe fruits, spikes, leaves, and veins. This species has been reputed to provide health effects on the cardiovascular, respiratory, nervous, metabolic, gastrointestinal, and reproductive systems. However, in many developing countries, quid from this species has been associated with side effects, which include the destruction of the teeth, impairment of oral hygiene, bronchial asthma, or oral cancer. Despite these side effects, which are also mentioned in this work, the present review collects the main results of biological properties of the phytochemicals in A. catechu. This study emphasizes the in vitro and in vivo antioxidant, antimicrobial, anticancer, and clinical effectiveness in humans. In this sense, A. catechu have demonstrated effectiveness in several reports through in vitro and in vivo experiments on disorders such as antimicrobial, antioxidant, or anticancer. Moreover, our findings demonstrate that this species presents clinical effectiveness on neurological disorders. Hence, A. catechu extracts could be used as a bioactive ingredient for functional food, nutraceuticals, or cosmeceuticals. However, further studies, especially extensive and comprehensive clinical trials, are recommended for the use of Areca in the treatment of diseases.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSalehi, Bahare; Konovalov, Dmitry A.; Fru, Pascaline; Kapewangolo, Petrina; Peron, Gregorio; Ksenija, Mileski S.; Cardoso, Susana M.; Pereira, Olívia R.; Nigam, Manisha; Nicola, Silvana; Pignata, Giuseppe; Rapposelli, Simona; Sestito, Simona; Anil Kumar, Nanjangud V.; Luz Cádiz‐Gurrea, María; Segura‐Carretero, Antonio; Mishra, Abhay P.; Sharifi‐Rad, Mehdi; Cho, William C.; Taheri, Yasaman; Setzer, William N.; Sharifi‐Rad, Javad (2020). Areca catechu - from farm to food and biomedical applications. Phytotherapy Research. ISSN 0951-418X. 34, p. 2140–2158pt_PT
dc.identifier.doi10.1002/ptr.6665pt_PT
dc.identifier.eissn1099-1573
dc.identifier.issn0951-418X
dc.identifier.urihttp://hdl.handle.net/10198/21945
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAlkaloidspt_PT
dc.subjectArecapt_PT
dc.subjectBetel nutpt_PT
dc.subjectHuman healthpt_PT
dc.subjectPhenolicspt_PT
dc.titleAreca catechu - from farm to food and biomedical applicationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage19pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titlePhytotherapy Researchpt_PT
person.familyNamePereira
person.givenNameOlívia R.
person.identifier145216
person.identifier.ciencia-idB312-AF21-D2FA
person.identifier.orcid0000-0002-6275-3134
person.identifier.ridH-1049-2014
person.identifier.scopus-author-id52264387000
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione8fdab9a-3ad6-47e6-b90c-7a37aabcb453
relation.isAuthorOfPublication.latestForDiscoverye8fdab9a-3ad6-47e6-b90c-7a37aabcb453

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