Logo do repositório
 
Publicação

Repurposing orange peel waste for limonene extraction using deep eutectic solvents for cosmetic applications

2026Artigo científico Acesso aberto
Ver registo simples
datacite.subject.fosCiências Naturais::Ciências Químicas
datacite.subject.fosEngenharia e Tecnologia::Biotecnologia Industrial
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
datacite.subject.sdg04:Educação de Qualidade
dc.contributor.authorArnič, Monika
dc.contributor.authorAndrejc, Kristina
dc.contributor.authorMartins, Mónia A. R.
dc.contributor.authorSosa, Filipe H.B.
dc.contributor.authorCoutinho, João A.P.
dc.contributor.authorLikozar, Blaž
dc.contributor.authorVicente, Filipa A.
dc.date.accessioned2026-02-18T15:32:52Z
dc.date.available2026-02-18T15:32:52Z
dc.date.issued2026
dc.description.abstractOrange peel waste, a byproduct of the citrus industry, can be valorized to obtain valuable compounds such as limonene, a terpene widely used in the food and cosmetics industry for its characteristic citrus aroma. Conventional extraction methods rely on organic solvents, which pose significant environmental concerns. To address this, deep eutectic solvents (DES) have emerged as a sustainable alternative. In this work, we screened various DES combinations using the COnductor-like Screening MOdel for Realistic Solvents (COSMO-RS), and the most promising systems containing compounds that are Generally Recognized as Safe (GRAS) or accepted by the Cosmetic Ingredient Review (CIR) were subsequently investigated experimentally. Polyethylene glycol 200 and 600 in combination with amino acids, sugars, carboxylic acids and urea were used for DES formulation. Among them, PEG200-urea showed a significantly higher extraction yield of limoneneper g of orange peel (2.7 mg g-1) which is approximately 1.4x higher than that obtained with the reference organic solvent, heptane (1.9 mg g-1). The limonene extracted with DES remained stable for at least five weeks when stored at room temperature and in the dark. In addition, hesperidin, a high-value flavonoid for cosmetic applications, was successfully quantified in the extracts, while bergapten (a phototoxic furanocoumarin) and several limonene oxidation products were not detected. Our results show that DES can achieve limonene yields comparable to, or higher than those of conventional extraction systems while presenting more sustainable metrics. This study emphasizes the potential of DES for the sustainable limonene extraction from dried orange peels and contributes to circular economy initiatives.eng
dc.description.sponsorshipThe authors acknowledge the financial support from the Slovenian Research Agency (research core funding P2-0152 and research projects BI-US/24-26-017, NC-0024 and NC-24002). The authors are also grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 and UIDP/00690/2020), SusTEC (LA/P/0007/2020), and CICECO-Aveiro Institute of Materials, (UIDB/50011/2020, UIDP/50011/2020, and LA/P/0006/2020). F. H. B. S. acknowledges FCT for the researcher contract CEECIND/07209/2022 under the Scientific Employment Stimulus – Individual Call 2022.
dc.identifier.citationArnic, Monika; Andrejc, Kristina; Martins, Mónia A. R.; Sosa, Filipe H. B.; Coutinho, Joao A. P.; Likozar, Blaz; Vicente, Filipa A. (2026). Repurposing orange peel waste for limonene extraction using deep eutectic solvents for cosmetic applications. Sustainable Chemistry and Pharmacy. ISSN 2352-5541. 50, p. 1-17
dc.identifier.doi10.1016/j.scp.2026.102339
dc.identifier.issn2352-5541
dc.identifier.urihttp://hdl.handle.net/10198/35778
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relationMountain Research Center
dc.relationAssociate Laboratory for Sustainability and Tecnology in Mountain Regions
dc.relationCICECO-Aveiro Institute of Materials
dc.relation.ispartofSustainable Chemistry and Pharmacy
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectConductor-like screening model for realistic
dc.subjectSolvents
dc.subjectWaste valorization
dc.subjectGreen extraction
dc.subjectCircular bioeconomy principles
dc.titleRepurposing orange peel waste for limonene extraction using deep eutectic solvents for cosmetic applicationseng
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUIDP/00690/2020
oaire.awardNumberLA/P/0007/2020
oaire.awardNumberUIDP/50011/2020
oaire.awardTitleMountain Research Center
oaire.awardTitleAssociate Laboratory for Sustainability and Tecnology in Mountain Regions
oaire.awardTitleCICECO-Aveiro Institute of Materials
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0007%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50011%2F2020/PT
oaire.citation.endPage17
oaire.citation.startPage1
oaire.citation.titleSustainable Chemistry and Pharmacy
oaire.citation.volume50
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameMartins
person.givenNameMónia A. R.
person.identifier.ciencia-id8117-0EEA-6B8E
person.identifier.orcid0000-0003-0748-1612
person.identifier.scopus-author-id56191802400
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublication18f906f2-efcf-456c-b638-c921bbebe284
relation.isAuthorOfPublication.latestForDiscovery18f906f2-efcf-456c-b638-c921bbebe284
relation.isProjectOfPublication0aac8939-28c2-46f4-ab6b-439dba7f9942
relation.isProjectOfPublication6255046e-bc79-4b82-8884-8b52074b4384
relation.isProjectOfPublicationee1756de-00fa-4114-831e-d61b00d3831f
relation.isProjectOfPublication.latestForDiscovery0aac8939-28c2-46f4-ab6b-439dba7f9942

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
Repurposing_waste.pdf
Tamanho:
4.33 MB
Formato:
Adobe Portable Document Format
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
1.75 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Ver/Abrir

Coleções

CIMO - Artigos em Revistas Indexados à WoS/Scopus