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Ficus carica L.: metabolic and biological screening.

dc.contributor.authorOliveira, Andreia P.
dc.contributor.authorValentão, Patrícia
dc.contributor.authorPereira, J.A.
dc.contributor.authorSilva, Branca M.
dc.contributor.authorTavares, Fernando
dc.contributor.authorAndrade, Paula B.
dc.date.accessioned2011-01-13T16:46:11Z
dc.date.available2011-01-13T16:46:11Z
dc.date.issued2009
dc.description.abstractFicus carica L. is one of the earliest cultivated fruit trees. In this work, metabolite profiling was performed on the leaves, pulps and peels of two Portuguese white varieties of F. carica (Pingo de Mel and Branca Tradicional). Phenolics and organic acids profiles were determined by HPLC/DAD and HPLC/UV, respectively. All samples presented a similar phenolic profile composed by 3-O- and 5-O-caffeoylquinic acids, ferulic acid, quercetin-3-O-glucoside, quercetin-3-O-rutinoside, psoralen and bergapten. 3-O-Caffeoylquinic acid and quercetin-3-O-glucoside are described for the first time in this species. Leaves’ organic acids profile presented oxalic, citric, malic, quinic, shikimic and fumaric acids, while in pulps and peels quinic acid was absent. The antioxidant potential of the different plant parts was checked. All materials exhibited activity against DPPH and nitric oxide radicals in a concentration-dependent way. However, only the leaves presented capacity to scavenge superoxide radical. Leaves were always the most effective part, which seems to be related with phenolics compounds. Additionally, acetylcholinesterase inhibitory capacity was evaluated, but no effect was observed. Antimicrobial potential was also assessed against several bacterial species, although no activity was noticed. This is the first study comparing the chemical composition and biological potential of F. carica pulps, peels and leaves.por
dc.identifier.citationOliveira, A.; Valentão, P.; Pereira, J.A.; Silva, B.M.; Tavares, F.; Andrade, P.B. (2009). Ficus carica L.: metabolic and biological screening. Food and Chemical Toxicology. ISSN 0278-6915. 47:11, p. 2841-2846por
dc.identifier.issn0278-6915
dc.identifier.urihttp://hdl.handle.net/10198/3111
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relation.publisherversionhttp://www.sciencedirect.com/science/journal/02786915por
dc.subjectFicus carica L.por
dc.subjectPhenolic compoundspor
dc.subjectOrganic acidspor
dc.subjectAntioxidantspor
dc.subjectAcetylcholinesterase inhibitionpor
dc.subjectAntimicrobial activitypor
dc.titleFicus carica L.: metabolic and biological screening.por
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage2846por
oaire.citation.issue47por
oaire.citation.startPage2841por
oaire.citation.titleFood and Chemical Toxicologypor
person.familyNamePereira
person.givenNameJosé Alberto
person.identifier.ciencia-id611F-80B2-A7C1
person.identifier.orcid0000-0002-2260-0600
person.identifier.ridL-6798-2014
person.identifier.scopus-author-id57204366348
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication7932162e-a2da-4913-b00d-17babbe51857
relation.isAuthorOfPublication.latestForDiscovery7932162e-a2da-4913-b00d-17babbe51857

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