Bioinks functionalized with natural extracts for 3D printing

Larraza, Izaskun; Santamaria-Echart, Arantzazu; Fernandes, Isabel Rodrigues; Barreiro, M.F.; Arbelaiz, Aitor; Eceiza, Arantaxa

Publication

Bioinks functionalized with natural extracts for 3D printing

2023Journal article

dc.contributor.author	Larraza, Izaskun
dc.contributor.author	Santamaria-Echart, Arantzazu
dc.contributor.author	Fernandes, Isabel Rodrigues
dc.contributor.author	Barreiro, M.F.
dc.contributor.author	Arbelaiz, Aitor
dc.contributor.author	Eceiza, Arantaxa
dc.date.accessioned	2024-03-21T11:39:37Z
dc.date.available	2024-03-21T11:39:37Z
dc.date.issued	2023
dc.description.abstract	In the search of materials valid for direct ink writing (DIW) 3D printing and with special interest for the biomedical and pharmaceutical applications, the development of bioactive inks for DIW is of great interest. For that purpose, in this work bioactive waterborne polyurethane–urea inks were prepared by addition of natural extracts (logwood, chestnut, and alder buckthorn) and cellulose nanofibers (CNF). The rheological behavior of the inks proved to be strongly dependent on the extract type and content, and the addition route used. Inks prepared by ex-situ incorporation of the extracts showed a strong gel-like behavior, as did inks prepared with chestnut and alder buckthorn extracts, which, in turn, hindered a continuous flow during the printing process, resulting in 3D printed parts with poor shape fidelity. On the other hand, inks prepared insitu and with logwood extract showed more facility to flow and higher homogeneity, which translated in better printability and better shape fidelity, further enhanced for CNF containing inks. 3D printed composites showed reinforced mechanical behavior, as well as in materials with enhanced antibacterial behavior. Overall, the possibility to successfully prepare bioactive inks valid for 3D printing was proven.	pt_PT
dc.description.sponsorship	Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. Financial support from the Basque Government (Grupos Consolidados (IT-1690-22), Elkartek (KK19-00048)) is acknowledged.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Larraza, Izaskun; Santamaria-Echart, Arantzazu; Fernandes, Isabel Rodrigues; Barreiro, M.F.; Arbelaiz, Aitor; Eceiza, Arantxa (2023). Bioinks functionalized with natural extracts for 3D printing. Journal of Polymers and the Environment. ISSN 1566-2543. 32:2, p. 982–999	pt_PT
dc.identifier.doi	10.1007/s10924-023-03044-0	pt_PT
dc.identifier.eissn	1572-8919
dc.identifier.issn	1566-2543
dc.identifier.uri	http://hdl.handle.net/10198/29639
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Springer	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Waterborne polyurethane–urea	pt_PT
dc.subject	3D printing	pt_PT
dc.subject	Natural extracts	pt_PT
dc.subject	Bioactive inks	pt_PT
dc.subject	Antimicrobial scaffolds	pt_PT
dc.title	Bioinks functionalized with natural extracts for 3D printing	pt_PT
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.endPage	18	pt_PT
oaire.citation.issue	2	pt_PT
oaire.citation.startPage	1	pt_PT
oaire.citation.title	Journal of Polymers and the Environment	pt_PT
oaire.citation.volume	32	pt_PT
person.familyName	Santamaria-Echart
person.familyName	Barreiro
person.givenName	Arantzazu
person.givenName	Filomena
person.identifier.ciencia-id	0C17-1E1F-2621
person.identifier.ciencia-id	3418-47D5-5746
person.identifier.orcid	0000-0003-0107-7301
person.identifier.orcid	0000-0002-6844-333X
person.identifier.rid	L-9802-2014
person.identifier.scopus-author-id	56725697700
person.identifier.scopus-author-id	57188719717
rcaap.rights	openAccess	pt_PT
rcaap.type	article	pt_PT
relation.isAuthorOfPublication	eb945e05-928f-45cb-ac27-04b4159ae31a
relation.isAuthorOfPublication	0391987c-ba90-488b-839a-153447ce1f0f
relation.isAuthorOfPublication.latestForDiscovery	0391987c-ba90-488b-839a-153447ce1f0f