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Compounds from wild mushrooms with antitumor potential

dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorVaz, Josiana A.
dc.contributor.authorVasconcelos, M. Helena
dc.contributor.authorMartins, Anabela
dc.date.accessioned2010-10-07T19:16:31Z
dc.date.available2010-10-07T19:16:31Z
dc.date.issued2010
dc.description.abstractFor thousands of years medicine and natural products have been closely linked through the use of traditional medicines and natural poisons. Mushrooms have an established history of use in traditional oriental medicine, where most medicinal mushroom preparations are regarded as a tonic, that is, they have beneficial health effects without known negative side-effects and can be moderately used on a regular basis without harm. Mushrooms comprise a vast and yet largely untapped source of powerful new pharmaceutical products. In particular, and most importantly for modern medicine, they represent an unlimited source of compounds which are modulators of tumour cell growth. Furthermore, they may have potential as functional foods and sources of novel molecules. We will review the compounds with antitumor potential identified so far in mushrooms, including low-molecular-weight (LMW, e.g. quinones, cerebrosides, isoflavones, catechols, amines, triacylglycerols, sesquiterpenes, steroids, organic germanium and selenium) and high-molecular-weight compounds (HMW, e.g. homo and heteroglucans, glycans, glycoproteins, glycopeptides, proteoglycans, proteins and RNA-protein complexes).por
dc.identifier.citationFerreira, Isabel C.F.R.; Vaz, Josiana A.; Vasconcelos, Helena; Martins, Anabela (2010). Compounds from wild mushrooms with antitumor potential. Anti-cancer Agents in Medicinal Chemistry. ISSN 1871-5206. 10:5, p. 424-436por
dc.identifier.issn1871-5206
dc.identifier.urihttp://hdl.handle.net/10198/2646
dc.language.isoengpor
dc.publisherBentham Sciencepor
dc.subjectMushroomspor
dc.subjectAntitumorpor
dc.subjectLow-molecular-weight compoundspor
dc.subjectHigh-molecular-weight compoundspor
dc.titleCompounds from wild mushrooms with antitumor potentialpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage436por
oaire.citation.startPage424por
oaire.citation.titleAnti-cancer Agents in Medicinal Chemistrypor
person.familyNameFerreira
person.familyNameVaz
person.familyNameMartins
person.givenNameIsabel C.F.R.
person.givenNameJosiana A.
person.givenNameAnabela
person.identifier144781
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id171B-88BA-64F5
person.identifier.ciencia-id7B18-A810-6B93
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-6989-1169
person.identifier.orcid0000-0001-6218-4413
person.identifier.ridE-8500-2013
person.identifier.ridG-5488-2013
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id16305323200
person.identifier.scopus-author-id7203013518
rcaap.rightsopenAccesspor
rcaap.typearticlepor
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relation.isAuthorOfPublication383370dd-10e5-40e6-9a15-f2201fe95581
relation.isAuthorOfPublication.latestForDiscovery1c1a2cb9-5a36-47ba-bca0-ffcbef28df18

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