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Food bioactive compounds and emerging techniques for their extraction: Polyphenols as a case study

dc.contributor.authorCâmara, José S.
dc.contributor.authorAlbuquerque, Bianca R.
dc.contributor.authorAguiar, Joselin
dc.contributor.authorCorrêa, Rúbia C.G.
dc.contributor.authorGonçalves, João L.
dc.contributor.authorGranato, Daniel
dc.contributor.authorPereira, Jorge A.M.
dc.contributor.authorBarros, Lillian
dc.contributor.authorFerreira, Isabel C.F.R.
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2021-12-02T16:31:52Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2021-12-02T16:31:52Z
dc.date.issued2021
dc.description.abstractExperimental studies have provided convincing evidence that food bioactive compounds (FBCs) have a positive biological impact on human health, exerting protective effects against noncommunicable diseases (NCD) including cancer and cardiovascular (CVDs), metabolic, and neurodegenerative disorders (NDDs). These benefits have been associated with the presence of secondary metabolites, namely polyphenols, glucosinolates, carotenoids, terpenoids, alkaloids, saponins, vitamins, and fibres, among others, derived from their antioxidant, antiatherogenic, anti-inflammatory, antimicrobial, antithrombotic, cardioprotective, and vasodilator properties. Polyphenols as one of the most abundant classes of bioactive compounds present in plant-based foods emerge as a promising approach for the development of efficacious preventive agents against NCDs with reduced side effects. The aim of this review is to present comprehensive and deep insights into the potential of polyphenols, from their chemical structure classification and biosynthesis to preventive effects on NCDs, namely cancer, CVDs, and NDDS. The challenge of polyphenols bioavailability and bioaccessibility will be explored in addition to useful industrial and environmental applications. Advanced and emerging extraction techniques will be highlighted and the high-resolution analytical techniques used for FBCs characterization, identification, and quantification will be considered.en_EN
dc.description.sponsorshipFCT (Fundação para a Ciência e a Tecnologia) through the CQM Base Fund-UIDB/00674/ 2020, the Programmatic Fund- UIDP/00674/2020, and the PhD fellowship SFRH/BD/116895/2016 granted to João Gonçalves. Madeira 14–20 Program, project PROEQUIPRAM-Reforço do Investimento em Equipamentos e Infraestruturas Científicas RAM (M1420-01-0145-FEDER-000008), ARDITIAgência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação through the project M1420-01-0145-FEDER-000005-Centro de Química da Madeira-CQM+ (Madeira 14–20 Program) and Project M1420-09-5369-FSE-000001 for the Post-Doctoral fellowship granted to JAMP. Núcleo Regional da Madeira da Liga Portuguesa Contra o Cancro (NRM-LPCC) for the professional internship granted to Joselin Aguiar. FCT for financial support by national funds FCT/MCTES to CIMO (UIDB/00690/2020). National funding by FCT, P.I., through the institutional scientific employment program-contract for L. Barros, and B.R. Albuquerque research grant (SFRH/BD/136370/2018). European Regional Development Fund (ERDF) through the Regional Operational Program North 2020, within the scope of the project Mobilizador Norte-01-0247-FEDER-024479: ValorNatural®. FEDER-Interreg España-Portugal programme for financial support through the project 0377_Iberphenol_ 6_E and TRANSCoLAB 0612_TRANS_CO_LAB_2_P. R.C.G. Corrêa is a research grant recipient of Cesumar Institute of Science Technology and Innovation (ICETI).
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationCâmara, José S.; Albuquerque, Bianca R.; Aguiar, Joselin; Corrêa, Rúbia C.G.; Gonçalves, João L.; Granato, Daniel; Pereira, Jorge A.M.; Barros, Lillian; Ferreira, Isabel C.F.R. (2021). Food bioactive compounds and emerging techniques for their extraction: Polyphenols as a case study. Foods. ISSN 2304-8158. 10:1, p.en_EN
dc.identifier.doi10.3390/foods10010037en_EN
dc.identifier.issn2304-8158
dc.identifier.urihttp://hdl.handle.net/10198/24442
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relationMadeira Chemistry Research Centre
dc.relationEstabelecimento do perfil metabólico e avaliação da citotoxicidade das novas substâncias psicoativas pertencentes à classe das catinonas sintéticas
dc.relationMountain Research Center
dc.relationNatural colorants based on anthocyanins obtained from bioresidues
dc.subjectBioavailability and bioaccessibilityen_EN
dc.subjectCanceren_EN
dc.subjectCardiovascular diseases (CVDs)en_EN
dc.subjectDisease protectionen_EN
dc.subjectFood bioactive compounds (FBCs)en_EN
dc.subjectNeurodegenerative diseases (NDs)en_EN
dc.subjectPolyphenolsen_EN
dc.titleFood bioactive compounds and emerging techniques for their extraction: Polyphenols as a case studyen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleMadeira Chemistry Research Centre
oaire.awardTitleEstabelecimento do perfil metabólico e avaliação da citotoxicidade das novas substâncias psicoativas pertencentes à classe das catinonas sintéticas
oaire.awardTitleMountain Research Center
oaire.awardTitleNatural colorants based on anthocyanins obtained from bioresidues
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00674%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/OE/SFRH%2FBD%2F116895%2F2016/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F136370%2F2018/PT
oaire.fundingStream6817 - DCRRNI ID
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oaire.fundingStream6817 - DCRRNI ID
person.familyNameAlbuquerque
person.familyNameCorrêa
person.familyNameBarros
person.familyNameFerreira
person.givenNameBianca R.
person.givenNameRúbia C.G.
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.identifier469085
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person.identifier.ciencia-id621C-B603-7519
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person.identifier.orcid0000-0002-9050-5189
person.identifier.orcid0000-0003-4910-4882
person.identifier.ridJ-3600-2013
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person.identifier.scopus-author-id57192311941
person.identifier.scopus-author-id37661286600
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person.identifier.scopus-author-id36868826600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
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