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Multicomponent chiral separations by analytical and preparative liquid chromatography

dc.contributor.authorRibeiro, António E.
dc.contributor.authorPais, Luís S.
dc.contributor.authorRodrigues, Alírio
dc.date.accessioned2014-01-15T10:20:05Z
dc.date.available2014-01-15T10:20:05Z
dc.date.issued2013
dc.description.abstractThis work will present a complete methodology concerning experimental, modelling and simulation results. Both the CHIRALPAK AD and CHIRALPAK IA CSP will be evaluated. The selection of the proper CSP/solvent combination for preparative operation will be fully study taking into account the screening strategy proposed by Zhang et al. Additional results include the measurement of nadolol stereoisomers solubilities, equilibrium adsorption data and fixed bed (breakthroughs) experiments. The complete screening of CSP/solvent combination will lead to the choice of the better solutions for the separation of nadolol stereoisomers, considering the target component or components to be obtained. Simulation and experimental results will be presented for the multicomponent separation of nadolol stereoisomers by multicolumn and Simulated Moving Bed adsorption processes.por
dc.identifier.citationRibeiro, António E.; Pais, L.S.; Rodrigues, A.E. (2013). Multicomponent chiral separations by analytical and preparative liquid chromatography. In 8º Encontro Nacional de Cromatografia, Sociedade Portugal. Universidade da Beira Interior, Covilhãpor
dc.identifier.urihttp://hdl.handle.net/10198/9154
dc.language.isoengpor
dc.peerreviewedyespor
dc.subjectChiral separationpor
dc.subjectNadololpor
dc.subjectChiralpak ADpor
dc.subjectChiralpak IApor
dc.titleMulticomponent chiral separations by analytical and preparative liquid chromatographypor
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceUniversidade da Beira Interior, Covilhãpor
oaire.citation.endPage104por
oaire.citation.startPage103por
oaire.citation.title8º Encontro Nacional de Cromatografia, Sociedade Portuguesa de Químicapor
person.familyNameRibeiro
person.familyNamePais
person.givenNameAntónio E.
person.givenNameLuís S.
person.identifier.ciencia-id3211-D5B0-870D
person.identifier.ciencia-id421E-0CCD-A84F
person.identifier.orcid0000-0003-4569-7887
person.identifier.orcid0000-0002-3000-2862
person.identifier.scopus-author-id23390701300
person.identifier.scopus-author-id6603930478
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
relation.isAuthorOfPublication52666376-f100-4407-87ef-dc5df3613761
relation.isAuthorOfPublicationc6d25534-8487-45b1-90af-d350f4e3ac55
relation.isAuthorOfPublication.latestForDiscovery52666376-f100-4407-87ef-dc5df3613761

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