Repository logo
 
Publication

Protective effects of phenolic constituents from Cytisus multiflorus, Lamium album L. and Thymus citriodorus on liver cells

2013Journal article Open access
Simple item page
dc.contributor.authorPereira, Olívia R.
dc.contributor.authorMacias, Rócio I.R.
dc.contributor.authorPerez, María J.
dc.contributor.authorMarín, Jose J.G.
dc.contributor.authorCardoso, Susana M.
dc.date.accessioned2013-09-16T09:28:07Z
dc.date.available2013-09-16T09:28:07Z
dc.date.issued2013
dc.description.abstractThe present study investigated the antioxidant and cytoprotective effects of purified ethanolic extracts of Cytisus multiflorus, Lamium album L. and Thymus citriodorus plants. These extracts showed high antioxidant activity in DPPH and reducing power assays. Using a model of chemical stress induced by potassium dichromate (DK) in human hepatoblastoma HepG2 cells, 50 ug/mL of C. multiflorus, L. album and T. citriodorus extracts decreased the rate of reactive oxygen species (ROS) production by 35%, 26% and 20%, respectively, when exposed to 25 mu M of DK. This effect was also observed for the treatment of cells with individual polyphenolic compounds determined in the extracts, or with mixtures prepared with individual polyphenolic compounds simulating the phenolic composition of the extracts. Additionally, the purified ethanolic extracts and the prepared polyphenolic mixtures showed a cytoprotective effect against DK-induced toxicity. The overall results emphasize the contribution of polyphenols in antioxidant and cytoprotective properties of the studied plants.por
dc.identifier.citationPereira, Olivia R.; Macias, Rocio I. R.; Perez, Maria J.; Marin, Jose J. G.; Cardoso, Susana M. (2013). Protective effects of phenolic constituents from Cytisus multiflorus, Lamium album L. and Thymus citriodorus on liver cells. ELSEVIER SCIENCE BV. ISSN 1756-4646. 5:3, p. 1170-1179por
dc.identifier.doi10.1016/j.jff.2013.03.014
dc.identifier.issn1756-4646
dc.identifier.urihttp://hdl.handle.net/10198/8758
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relationSFRH/PROTEC/49600/ 2009
dc.relationStrategic Project - UI 681 - 2011-2012
dc.subjectCytisus multifloruspor
dc.subjectLamium album L.por
dc.subjectThymus citriodoruspor
dc.subjectPhenolic compoundspor
dc.subjectCytoprotectionpor
dc.subjectAntioxidant activitypor
dc.titleProtective effects of phenolic constituents from Cytisus multiflorus, Lamium album L. and Thymus citriodorus on liver cellspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 681 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0681%2F2011/PT
oaire.citation.conferencePlaceAMSTERDAM, NETHERLANDSpor
oaire.citation.endPage1179por
oaire.citation.startPage1170por
oaire.citation.titleJournal of Functional Foodspor
oaire.citation.volume5por
oaire.fundingStream6817 - DCRRNI ID
person.familyNamePereira
person.givenNameOlívia R.
person.identifier145216
person.identifier.ciencia-idB312-AF21-D2FA
person.identifier.orcid0000-0002-6275-3134
person.identifier.ridH-1049-2014
person.identifier.scopus-author-id52264387000
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublicatione8fdab9a-3ad6-47e6-b90c-7a37aabcb453
relation.isAuthorOfPublication.latestForDiscoverye8fdab9a-3ad6-47e6-b90c-7a37aabcb453
relation.isProjectOfPublication762f76ce-d7b9-44dc-870e-3199f6968094
relation.isProjectOfPublication.latestForDiscovery762f76ce-d7b9-44dc-870e-3199f6968094

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Protective effects of phenolic constituents from Cmultiflorus, Lalbum and T citriodorus on liver cells.pdf
Size:
642.7 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIMO - Artigos em Revistas Indexados à WoS/Scopus