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Mushroom-based cosmeceutical ingredients: Microencapsulation and in vitro release profile

dc.contributor.authorTaofiq, Oludemi
dc.contributor.authorHeleno, Sandrina A.
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorFernandes, Isabel P.
dc.contributor.authorAlves, Maria José
dc.contributor.authorBarros, Lillian
dc.contributor.authorGonzález-Paramás, Ana María
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarreiro, M.F.
dc.date.accessioned2018-02-19T10:00:00Z
dc.date.accessioned2019-02-04T17:01:17Z
dc.date.available2018-01-19T10:00:00Z
dc.date.available2019-02-04T17:01:17Z
dc.date.issued2018
dc.description.abstractMushrooms can be used as a source of cosmeceutical ingredients. Agaricus bisporus and Pleurotus ostreatus ethanolic extracts present important bioactive properties, but withsome compounds showingeasy oxidation and degradation. In the present work, microencapsulation by atomization/coagulation technique was used toprotect the extracts. The obtained microspheres were characterised in terms of morphology, particle size distribution and encapsulation efficiency. Microencapsulated extracts were incorporated into a semi-solid base cream and their performance compared with the use of the free forms in terms of bioactivity, and in vitro release using the cosmetic matrix and real time conditions (up to 6 months). The physico-chemical properties (colour and pH) of the developed formulations were also monitored over the same time period. The cosmeceutical formulations containing free extracts displayed bioactivity. For the formulations prepared with the encapsulated forms, the release of the extracts was achieved and anti-tyrosinase and antimicrobial activities were observed, while for the antioxidant activity, the extract release over the time was not sufficient to exert an effect. Overall, the use of mushroom extracts in free or encapsulated forms can be an option in cosmeceutical formulations, and the encapsulated forms can allow a controlled release leading to bioactivity control.en_EN
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2013) and S.A. Heleno (SFRH/BPD/101413/2014). This work was also financially supported by Project POCI-01-0145-FEDER-006984 – Associate Laboratory LSRE-LCM funded by FEDER through COMPETE2020 - Programa Operacional Competitividade e Internacionalização (POCI) – and by national funds through FCT and project NORTE-01-0145-FEDER-000006, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). The authors are grateful to FEDER-Interreg España-Portugal programme for financial support through the project 0377_Iberphenol_6_E. This work was also funded by the European Structural and Investment Funds (FEEI) through the Regional Operational Program North 2020, within the scope of Mobilizing Project ValorNatural®. This work is funded by the European Agricultural Fund for Rural Development (EAFRD), through the Rural Development Program (PDR2020), within the scope of Project MicoCoating (PDR2020-101-031472).
dc.description.versioninfo:eu-repo/semantics/publishedVersionen_EN
dc.identifier.citationTaofiq, Oludemi; Heleno, Sandrina A.; Calhelha, Ricardo C.; Fernandes, Isabel P.; Alves, Maria José; Barros, Lillian; González-Paramás, A.M.; Ferreira, Isabel C.F.R.; Barreiro, M.F. (2018). Mushroom-based cosmeceutical ingredients: Microencapsulation and in vitro release profile. Industrial Crops and Products. ISSN 0926-6690. 124, p. 44-52en_EN
dc.identifier.doi10.1016/j.indcrop.2018.07.057en_EN
dc.identifier.issn0926-6690
dc.identifier.urihttp://hdl.handle.net/10198/18663
dc.language.isoeng
dc.peerreviewedyesen_EN
dc.relation0377_Iberphenol_6_E
dc.relationObtaining of mycosterols to develop new functionalized foods: extraction, refinement, stabilization and incorporation into dairy products
dc.relationPDR2020-101-031472
dc.subjectBioactive propertiesen_EN
dc.subjectControlled releaseen_EN
dc.subjectCosmeceuticalsen_EN
dc.subjectMicroencapsulationen_EN
dc.subjectMushroom extractsen_EN
dc.titleMushroom-based cosmeceutical ingredients: Microencapsulation and in vitro release profileen_EN
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleObtaining of mycosterols to develop new functionalized foods: extraction, refinement, stabilization and incorporation into dairy products
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAGR%2F00690%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBPD%2F101413%2F2014/PT
oaire.fundingStream5876
person.familyNameHeleno
person.familyNameCalhelha
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person.familyNameAlves
person.familyNameBarros
person.familyNameFerreira
person.familyNameBarreiro
person.givenNameSandrina A.
person.givenNameRicardo C.
person.givenNameIsabel P.
person.givenNameMaria José
person.givenNameLillian
person.givenNameIsabel C.F.R.
person.givenNameFilomena
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person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-6844-333X
person.identifier.ridL-5951-2014
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project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccessen_EN
rcaap.typearticleen_EN
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