Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. caespititius

Afonso, Andrea Luísa Fernandes; Pereira, Olívia R.; Silva, Artur; Cardoso, Susana M.

Publication

Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. caespititius

2017Conference object

dc.contributor.author	Afonso, Andrea Luísa Fernandes
dc.contributor.author	Pereira, Olívia R.
dc.contributor.author	Silva, Artur
dc.contributor.author	Cardoso, Susana M.
dc.date.accessioned	2017-12-20T09:47:35Z
dc.date.available	2017-12-20T09:47:35Z
dc.date.issued	2017
dc.description.abstract	The genus Thymus, belonging to Lamiaceae family, is rich in medicinal and aromatic species and well-known by several health promoting activities [1,2]. Despite this genus has been extensively studied, some species remain unexploited. In this study, Thymus herba-barona, Thymus pseudolanuginosus and Thymus caespititius decoctions were screened for their phenolic constituents by ultra-high performance liquid chromatography coupled to diode array detector and an electrospray mass spectrometer (UHPLC-DAD-ESI-MSn) operating in negative mode. The three aqueous extracts were rich in caffeic acid derivatives, mainly rosmarinic acid (MW 359) and its structural isomers, that accounted for 55.8 ± 2.8 mg/g in T. herba-barona and 40.2 ± 0.9 and 43.2 ± 3.2 mg/g in T. pseudolanuginosus and T. caespititius, respectively. In turn, other depsides were differently distributed in the three Thyme extracts: while dihydro-salvianolic acid B (MW 716 Da) and caffeoyl rosmarinic acid were particularly representative in T. herba-barona, salvianolic acids K ([M-H]− at m/z 555 493 359) and B ( [M-H]− at m/z 717 519 475) were found in moderate amounts in T. caespititius extract. On the other hand, T. pseudolanuginosus was clearly distinguished by its richness in the flavone luteolin-O-glucuronide ([M − H]− at m/z 461→285). Overall, this work is an important contribution for the phytochemical characterization of these three Thymus species, which are poorly explored.	pt_PT
dc.description.sponsorship	The authors acknowledge FCT the European Union, QREN, FEDER, COMPETE, for funding the Organic Chemistry Research Unit (QOPNA) (project PEst-C/QUI/UI0062/2013; FCOMP-01-0124-FEDER-037296)	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Afonso, Andrea F.; Pereira, Olívia R.; Silva, Artur; Cardoso, Susana M. (2017). Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. Caespititius. In 10º Encontro Nacional de Cromatografia. Bragança. ISBN 978-972-745-234-7	pt_PT
dc.identifier.uri	http://hdl.handle.net/10198/14783
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Instituto Politécnico de Bragança	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Thymus	pt_PT
dc.subject	Chemical characterization	pt_PT
dc.subject	T. herba-barona	pt_PT
dc.subject	T. pseudolanuginosus	pt_PT
dc.subject	T. caespititius	pt_PT
dc.title	Chemical characterization of three Thymus species: T. herba-barona, T. pseudolanuginosus and T. caespititius	pt_PT
dc.type	conference object
dspace.entity.type	Publication
oaire.awardURI	info:eu-repo/grantAgreement/FCT/COMPETE/PEst-C%2FQUI%2FUI0062%2F2013/PT
oaire.citation.conferencePlace	Bragança	pt_PT
oaire.citation.startPage	72	pt_PT
oaire.citation.title	10th Chromatography Meeting	pt_PT
oaire.fundingStream	COMPETE
person.familyName	Afonso
person.familyName	Pereira
person.givenName	Andrea Luísa Fernandes
person.givenName	Olívia R.
person.identifier	145216
person.identifier.ciencia-id	9C1D-41E7-9BBF
person.identifier.ciencia-id	B312-AF21-D2FA
person.identifier.orcid	0000-0002-8858-1617
person.identifier.orcid	0000-0002-6275-3134
person.identifier.rid	H-1049-2014
person.identifier.scopus-author-id	36766901000
person.identifier.scopus-author-id	52264387000
project.funder.identifier	http://doi.org/10.13039/501100001871
project.funder.name	Fundação para a Ciência e a Tecnologia
rcaap.rights	openAccess	pt_PT
rcaap.type	conferenceObject	pt_PT
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