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Centauri honey: a promising medicinal ingredient?

dc.contributor.authorFilipe, Márcia Santos
dc.contributor.authorPires, Tânia C.S.P.
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorDiaz-Lanza, Ana María
dc.contributor.authorVilas-Boas, Miguel
dc.contributor.authorFalcão, Soraia
dc.contributor.authorRijo, Patrícia
dc.date.accessioned2024-05-06T14:24:51Z
dc.date.available2024-05-06T14:24:51Z
dc.date.issued2023
dc.description.abstractHoney is a natural product that has been used over the centuries as a medicine due to its biological activities. Centauri Cave Nymph Honey is a Cave honey extracted from 2500 meters high altitude above sea level from a deep cave by professional speleologists and is located at Caucasus Mountains of Turkey. The Apis mellifera Caucasica bee colony is located 50 kilometers away from human residences, ensuring its isolation from other colonies and maintaining a varroa mite-free status. The aim of this work is to analyze the physicochemical parameters and the bioactivity of Centauri honey. The physiochemical parameters that have been examined include color, moisture content, conductivity, pH, acidity, HMF (5-hydroxymethylfurfural), diastase index, and proline. In addition, it was also evaluated the ash, protein, sugars, carbohydrates, and energy. The biological activity was evaluated through the antioxidant (TBARS), antimicrobial activities and cytotoxicity in different cell lines (AGS, CaCo-2, MCF-7, NCI-H460, PLP2, HFF-2, and HaCat), and anti-inflammatory activity (RAW 264.7 macrophages). Ongoing research is focusing on the potential protetive effects of consuming Centauri Cave Honey against lung and prostate cancers. In vivo studies are expected to shed more ligt on the additional health benefits that this honey may offer.pt_PT
dc.description.sponsorshipThe authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 and UIDP/00690/2020) and SusTEC (LA/P/0007/2021).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFilipe, Márcia Santos; Pires, Tânia C.S.P.; Calhelha, Ricardo C.; Diaz-Lanza, Ana María; Vilas-Boas, Miguel; Falcão, Soraia; Rijo, Patrícia (2023). Centauri honey: a promising medicinal ingredient? In III Bio Natural-Bioactive Natural Products Research Meeting: abstract book. Lisboa.pt_PT
dc.identifier.urihttp://hdl.handle.net/10198/29719
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherUniversidade Lusófonapt_PT
dc.relationLA/P/0007/2021pt_PT
dc.relationMountain Research Center
dc.relationMountain Research Center
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleCentauri honey: a promising medicinal ingredient?pt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleMountain Research Center
oaire.awardTitleMountain Research Center
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00690%2F2020/PT
oaire.citation.conferencePlaceLisboapt_PT
oaire.citation.titleIII Bio Natural-Bioactive Natural Products Research Meeting: abstract book. Lisboa.pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNamePires
person.familyNameCalhelha
person.familyNameVilas-Boas
person.familyNameFalcão
person.givenNameTânia C.S.P.
person.givenNameRicardo C.
person.givenNameMiguel
person.givenNameSoraia
person.identifier2118829
person.identifier1693134
person.identifier711432
person.identifier.ciencia-id321E-2D96-00CA
person.identifier.ciencia-idF313-E3CE-554E
person.identifier.ciencia-idA918-C6FF-81A4
person.identifier.ciencia-idD41A-6BED-4CBB
person.identifier.orcid0000-0002-3954-3833
person.identifier.orcid0000-0002-6801-4578
person.identifier.orcid0000-0002-8665-5280
person.identifier.orcid0000-0003-3735-6951
person.identifier.ridQ-2842-2018
person.identifier.ridJ-2172-2014
person.identifier.ridI-5949-2013
person.identifier.scopus-author-id57057440000
person.identifier.scopus-author-id6507978333
person.identifier.scopus-author-id6602648497
person.identifier.scopus-author-id14832459200
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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