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Plant alkaloids: production, extraction, and potential therapeutic properties

2023Book part Restricted access
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dc.contributor.authorPereira, Antia Gonzalez
dc.contributor.authorCassani, Lucia
dc.contributor.authorGarcia-Oliveira, Paula
dc.contributor.authorOtero, Paz
dc.contributor.authorMansoor, Sepidar
dc.contributor.authorEchave Álvarez, Javier
dc.contributor.authorXiao, Jianbo
dc.contributor.authorSimal-Gandara, Jesus
dc.contributor.authorPrieto Lage, Miguel A.
dc.date.accessioned2024-01-03T09:56:50Z
dc.date.available2024-01-03T09:56:50Z
dc.date.issued2023
dc.description.abstractAlkaloids are a type of secondary metabolites that can be found in different parts of plants. This group of compounds is diverse and can be divided into nine subgroups: pyridine, tropane, isoquinoline, phenanthrene, phenylethylamine, indole, purine, imidazole, and terpenoids. Most of these compounds are recognized for their anti-inflammatory, antitumor, antibacterial, antifungal, and antiviral activities, among others. Although more than 27,000 alkaloids have been described up to date, the search for novel compounds with promising therapeutic properties is a hot topic among researchers worldwide. In this line, the production of the currently marketed plant alkaloids including extraction methods, isolation, and purification is reviewed in this chapter. In addition, a deep description of different groups of alkaloids in terms of their chemical structure, plant source, and uses is also presented. Recent advances in the therapeutic potential and biological activities of this vast group of phytochemicals are also included.pt_PT
dc.description.sponsorshipThe research leading to these results was supported by MICINN supporting the Ramón y Cajal grant for M.A. Prieto (RYC-2017-22891); by Xunta de Galicia supporting the program EXCELENCIA-ED431F 2020/12, the post-doctoral grant of L. Cassani (ED481B-2021/ 152), and the pre-doctoral grants of P. Garcia-Oliveira (ED481A-2019/295), and A.G. Pereira (ED481A-2019/0228); by the EcoChestnut Project (Erasmus+ KA202) that supports the work of J. Echave; and by the Bio Based Industries Joint Undertaking (JU) under grant agreement No 888003 UP4HEALTH Project (H2020-BBI-JTI-2019) that supports the work of P. Otero. JU receives support from the European Union’s Horizon 2020 research and innovation program and the Bio Based Industries Consortium. Authors are grateful to Ibero-American Program on Science and Technology (CYTED—AQUA-CIBUS, P317RT0003). The project SYSTEMIC Knowledge hub on Nutrition and Food Security has received funding from national research funding parties in Belgium (FWO), France (INRA), Germany (BLE), Italy (MIPAAF), Latvia (IZM), Norway (RCN), Portugal (FCT), and Spain (AEI) in a joint action of JPI HDHL, JPI-OCEANS, and FACCE-JPI launched in 2019 under the ERA-NET ERA-HDHL (n° 696295).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPereira, Antia Gonzalez; Cassani, Lucia; Garcia-Oliveira, Paula; Otero, Paz; Mansoor, Sepidar; Echave, Javier; Xiao, Jianbo; Simal-Gandara, Jesus; Prieto Lage, Miguel A. (2023). Plant alkaloids: production, extraction, and potential therapeutic properties. Natural Secondary Metabolites: From Nature, Through Science, to Industry. Cham: Springer Nature. p. 157-197. ISBN 978-3-031-18586-1pt_PT
dc.identifier.doi10.1007/978-3-031-18587-8_6pt_PT
dc.identifier.isbn978-3-031-18586-1
dc.identifier.isbn978-3-031-18587-8 (eBook)
dc.identifier.urihttp://hdl.handle.net/10198/29020
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Naturept_PT
dc.relationSustainable and cost-effective production process for the upcycling of olive, grape and nut by-products into 4 natural and healthy ingredients for nutraceutical and cosmetic applications
dc.relationERA-NET Biomarkers for Nutrition and Health implementing the JPI HDHL objectives
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBiological propertiespt_PT
dc.subjectClassificationpt_PT
dc.subjectExtractionpt_PT
dc.subjectIsolationpt_PT
dc.subjectSecondary metabolitept_PT
dc.titlePlant alkaloids: production, extraction, and potential therapeutic propertiespt_PT
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleSustainable and cost-effective production process for the upcycling of olive, grape and nut by-products into 4 natural and healthy ingredients for nutraceutical and cosmetic applications
oaire.awardTitleERA-NET Biomarkers for Nutrition and Health implementing the JPI HDHL objectives
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/888003/EU
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/696295/EU
oaire.citation.endPage197pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage157pt_PT
oaire.citation.titleNatural Secondary Metabolites: From Nature, Through Science, to Industrypt_PT
oaire.fundingStreamH2020
oaire.fundingStreamH2020
person.familyNamePrieto Lage
person.givenNameMiguel A.
person.identifier107688
person.identifier.ciencia-id221E-1E00-AB74
person.identifier.orcid0000-0002-3513-0054
person.identifier.ridG-4516-2011
person.identifier.scopus-author-id35937495700
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
project.funder.nameEuropean Commission
rcaap.rightsrestrictedAccesspt_PT
rcaap.typebookPartpt_PT
relation.isAuthorOfPublication13260615-fd28-4b8b-9dd4-8a8466007579
relation.isAuthorOfPublication.latestForDiscovery13260615-fd28-4b8b-9dd4-8a8466007579
relation.isProjectOfPublication9980c0d6-0317-49a0-a44d-b8aedf2294a5
relation.isProjectOfPublication160ee2e3-b63a-4185-ac5d-5deb7281fef2
relation.isProjectOfPublication.latestForDiscovery9980c0d6-0317-49a0-a44d-b8aedf2294a5

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