| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 172.72 KB | Adobe PDF |
Advisor(s)
Abstract(s)
The electronic tongue is a multi-sensors system used to identify the basic standards of taste, such as sweet, salty, sour and bitter, at levels not detectable by humans. Although the main purpose of electronic tongue is the qualitative analysis, the quantitative analysis of substances in a liquid matrix is also possible, having been the subject of these preliminary studies the application of electronic tongue to pharmaceutical products. In this way, the aim of the current study was the quantitative analysis of ascorbic acid (AA) and acetylsalicylic acid (ASA) in several commercial preparations using an electronic tongue.
Methods: For that, solutions of standard compounds or of commercial preparations contain ascorbic acid and acetylsalicylic acid were analizes by an electronic tongue. The obtained data were using to determine the concentrations of the solutions thought através do multiple linear regression method.
Results: The preliminary tests showed that it is possible to quantify the ascorbic acid in effervescent formulations of vitamin C, using the predictor model obtained by multiple linear regression. In the case of acetylsalicylic acid it was verified that the matrix of the analgesics or antipyretics drugs significantly affect the signs of the electronic tongue.
Conclusions: The electronic tongue can be used determined ascorbic acid in effervescent formulations while it is necessary developed more selective sensors to acetylsalicylic acid in order to improve the predictive power of electronic tongue quantification of this compound.
Description
Keywords
Electronic tongue Quantitive analysis Ascorbic acid Acetylsalicylic acid
Citation
Pereira, Olívia R.; Gomes, Cláudia; Gonçalves, Cristina; Borlido, Diana; Batista, Marta; Teixeira, Tatiana; Dias, Luís G. (2014). Determination of ascorbic acid and acetylsalicylic acid in commercial preparations using an electronic tongue. Atención Primaria. ISSN 0212-6567. 46 (Esp Cong 1), p. 85-85