Repository logo
 
Publication

Geranyl acetate synthesis in a packed-bed reactor catalyzed by novozym in supercritical carbon dioxide and in supercritical ethane

2011Journal article Restricted access
Simple item page
dc.contributor.authorCouto, Ricardo
dc.contributor.authorVidinha, Pedro
dc.contributor.authorPeres, Célia Peres
dc.contributor.authorRibeiro, Adriano S.
dc.contributor.authorFerreira, Olga
dc.contributor.authorOliveira, Manuela V.
dc.contributor.authorMacedo, Eugénia A.
dc.contributor.authorLoureiro, José M.
dc.contributor.authorBarreiros, Susana F.
dc.date.accessioned2011-04-04T14:26:58Z
dc.date.available2011-04-04T14:26:58Z
dc.date.issued2011
dc.description.abstractThe esterification reaction of geraniol with acetic acid (100 mM/100 mM) catalyzed by immobilized Candida antarctica lipase B (Novozym 435) was studied in supercritical carbon dioxide (sc-CO2) and in sc-ethane in a packed-bed reactor(PBR). In sc-CO2 it was easy to adjust the water activity (aw) in the reaction mixture to levels leading to good enzyme performance. Enzyme stability was high and steady-state conversions could be achieved that exceeded the largest conversions measured in batch stirred-tank reactors (BSTRs), which is probably due to the lower aw levels achieved in the PBR. In sc-ethane, where the solubility of water is lower, high steady-state conversions could be attained only by preventing the accumulation on the enzyme bed of the water produced during reaction. The kinetic parameters for the reaction in sc-CO2 were determined using previously published data obtained in a BSTR, and a model was developed for the PBR that included those kinetic parameters. This model was able to predict with reasonable accuracy the behavior of the PBR. Slight differences were observed for some operating regions, probably due to the influence of aw in the activity of the enzyme, which is not included in the model.por
dc.description.sponsorshipThis work was supported by Fundação para a Ciência e Tecnologia (FCT, Portugal) through grants SFRH/BD/13084/2003 (A.S.R.) and SFRH/BPD/41546/2007 (P.V.), FEDER, and by the European Commission in the framework of the Marie Curie Research Training Network “Green Chemistry in Supercritical Fluids: Phase Behaviour, Kinetics and Scale-up” (EC Contract No. MRTN-CT-2004-504005). We thank Novo Nordisk Bioindustrial, Spain, for the gift of Novozym 435.por
dc.identifier.citationCouto, Ricardo; Vidinha, Pedro; Peres, Célia Peres; Ribeiro, Adriano S.; Ferreira, Olga; Oliveira, Manuela V.; Macedo, Eugénia A.; Loureiro, José M.; Barreiros, Susana (2011). Geranyl acetate synthesis in a packed-bed reactor catalyzed by novozym in supercritical carbon dioxide and in supercritical ethane. Industrial & Engineering Chemistry Research. ISSN 0888-5885. 50:4, p.1938-1946.por
dc.identifier.doi10.1021/ie101489j
dc.identifier.urihttp://hdl.handle.net/10198/3930
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherAmerican Chemical Societypor
dc.relationESTUDOS DE CATÁLISE ENZIMÁTICA EM MEIO SUPERCRÍTICO
dc.subjectEnzymaticpor
dc.subjectCatalysispor
dc.titleGeranyl acetate synthesis in a packed-bed reactor catalyzed by novozym in supercritical carbon dioxide and in supercritical ethanepor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleESTUDOS DE CATÁLISE ENZIMÁTICA EM MEIO SUPERCRÍTICO
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F13084%2F2003/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F41546%2F2007/PT
oaire.citation.endPage1946por
oaire.citation.startPage1938por
oaire.citation.titleIndustrial & Engineering Chemistry Researchpor
oaire.fundingStreamSFRH
person.familyNameFerreira
person.givenNameOlga
person.identifier.ciencia-id9F1D-C75A-4A54
person.identifier.orcid0000-0001-8414-3479
person.identifier.ridM-4567-2013
person.identifier.scopus-author-id57203083219
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication59e0c608-0c21-4191-af5e-529d21970399
relation.isAuthorOfPublication.latestForDiscovery59e0c608-0c21-4191-af5e-529d21970399
relation.isProjectOfPublicationd71841f5-cd66-4fab-bf77-1ca2d8c73e8c
relation.isProjectOfPublication0dcb08e9-aeb1-4cdb-9237-97114fcda4ea
relation.isProjectOfPublication.latestForDiscoveryd71841f5-cd66-4fab-bf77-1ca2d8c73e8c

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Couto_IECR_2011.pdf
Size:
1.71 MB
Format:
Adobe Portable Document Format
Description:
Documento principal
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIMO - Artigos em Revistas Indexados à WoS/Scopus