Repository logo
 
Publication

Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice

2023Journal article Open access
Simple item page
dc.contributor.authorSilva, Tamires Barlati Vieira
dc.contributor.authorDias, Maria Inês
dc.contributor.authorPereira, Carla
dc.contributor.authorMandim, Filipa
dc.contributor.authorIvanov, Marija
dc.contributor.authorSoković, Marina
dc.contributor.authorFerreira, Isabel C.F.R.
dc.contributor.authorBarros, Lillian
dc.contributor.authorSeixas, Flávio Augusto Vicente
dc.contributor.authorBracht, Adelar
dc.contributor.authorPeralta, Rosane M.
dc.date.accessioned2023-03-02T15:45:40Z
dc.date.available2023-03-02T15:45:40Z
dc.date.issued2023
dc.description.abstractA variety of the classic green tea plant, Camellia sinensis, was developed and is exclusive to Kenya. Due to high content of anthocyanin polyphenols in its leaves, the beverage obtained from this variety is purple in color and is the origin of the name purple tea. This work had two main purposes. The first one was to identify and quantify the major anthocyanin polyphenols in a hot water aqueous extract of the purple tea leaves. The second one was to test the hypothesis if this extract is capable of inhibiting triglyceride absorption considering that anthocyanin polyphenolics have been frequently associated to antilipidemic effects. Parallel experiments were always done with a similar green tea extract for comparison purposes. The antioxidant, anti-inflammatory, and cytotoxic activities of both tea varieties are similar. The purple tea extract, however, was strongly inhibitory toward the pancreatic lipase (minimal IC50 = 67.4 mu g mL(-1)), whereas the green tea preparation was a weak inhibitor. Triglyceride digestion in mice was inhibited by the purple tea extract starting at 100 mg kg(-1) dose and with a well-defined dose dependence. Green tea had no effect on triglyceride digestion at doses up to 500 mg kg(-1). The latter effect is probably caused by several components in the purple tea extract including non-anthocyanin and anthocyanin polyphenols, the first ones acting solely via the inhibition of the pancreatic lipase and the latter by inhibiting both the lipase and the transport of free fatty acids from the intestinal lumen into the circulating blood. The results suggest that the regular consumption of Kenyan purple tea can be useful in the control of obesity.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSilva, Tamires Barlati Vieira; Dias, Maria Inês; Pereira, Carla; Mandim, Filipa; Ivanov, Marija; Soković, Marina; Ferreira, Isabel C.F.R.; Barros, Lillian; Seixas, Flávio Augusto Vicente; Bracht, Adelar; Peralta, Rosane M.. (2023). Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice. Food & Function. eISSN 2042-650X. 14:3, p. 1761-1772pt_PT
dc.identifier.doi10.1039/d2fo02442j
dc.identifier.eissn2042-650X
dc.identifier.issn2042-6496
dc.identifier.urihttp://hdl.handle.net/10198/27414
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherRoyal Society of Chemistrypt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectVitro gastrointestinal digestionpt_PT
dc.subjectGreen teapt_PT
dc.subjectAntioxidant activitypt_PT
dc.subjectExtract improvespt_PT
dc.subjectAnthocyaninspt_PT
dc.subjectPolyphenols
dc.subjectRats
dc.subjectRich
dc.subjectApoptosis
dc.subjectProfile
dc.titlePurple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in micept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleFood & Functionpt_PT
person.familyNameDias
person.familyNamePereira
person.familyNameMandim
person.familyNameFerreira
person.familyNameBarros
person.givenNameMaria Inês
person.givenNameCarla
person.givenNameFilipa
person.givenNameIsabel C.F.R.
person.givenNameLillian
person.identifier1415151
person.identifier144781
person.identifier469085
person.identifier.ciencia-id2A13-4BE6-C7CF
person.identifier.ciencia-idEF10-2739-2B70
person.identifier.ciencia-idF318-9049-EB99
person.identifier.ciencia-id9418-CF95-9919
person.identifier.ciencia-id9616-35CB-D001
person.identifier.orcid0000-0001-8744-7814
person.identifier.orcid0000-0003-0093-771X
person.identifier.orcid0000-0002-6494-2326
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0002-9050-5189
person.identifier.ridM-8242-2013
person.identifier.ridK-1629-2016
person.identifier.ridE-8500-2013
person.identifier.ridJ-3600-2013
person.identifier.scopus-author-id54388787000
person.identifier.scopus-author-id55627876424
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id35236343600
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication7ca8432b-e7f4-4116-a56e-9eba0d4403bd
relation.isAuthorOfPublicatione07a8e12-52bb-47c5-bae7-41a5f648213b
relation.isAuthorOfPublicationbcc274d4-7e6c-46a8-8e49-2752f9dbfbcd
relation.isAuthorOfPublicationbd0d1537-2e03-41fb-b27a-140af9c35db8
relation.isAuthorOfPublication3af07ffe-f914-48ba-a5d5-efcf70fdce01
relation.isAuthorOfPublication.latestForDiscovery7ca8432b-e7f4-4116-a56e-9eba0d4403bd

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Purple tea chemical characterization and evaluation.pdf
Size:
1.69 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIMO - Artigos em Revistas Indexados à WoS/Scopus